Post Doctoral Fellow - Oncology Research

The Amgen Postdoctoral program is committed to providing future scientists with an enriching environment to inspire innovation that will contribute to the breakthroughs in basic science and the development of human therapeutics.

Dr. Wenjun Ouyang's lab is seeking a highly motivated postdoctoral candidate to perform independent research to study the regulation and function of T cells in autoimmunity and in cancer. Particularly, we are interested in understanding how different antigens in either autoimmune diseases or cancers control the fate of T cell mediated immune responses and tolerance, as well as the role of TCR diversity in these processes. In addition, we are also interested in the identification of novel regulatory pathways based human genetic information, single cell RNAseq studies and dissecting their molecular mechanisms by utilizing various in vitro and in vivo systems.

Selected publications from Dr. Wenjun Ouyang's lab:

Zhang L, Yu X, Zheng L, Zhang Y, Li Y, Fang Q, Gao R, Kang B, Zhang Q, Huang JY, Konno H, Guo X, Ye Y, Gao S, Wang S, Hu X, Ren X, Shen Z*, Ouyang W*, Zhang Z*. (2018) Lineage tracking reveals dynamic relationships of T cells in colorectal cancer. *Corresponding authors. Nature 564(7735):268-272.

Ouyang W, O'Garra A. (2019) IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation. Immunity.50(4):871-891.

Zheng C, Zheng L, Yoo JK, Guo H, Zhang Y, Guo X, Kang B, Hu R, Huang JY, Zhang Q, Liu Z, Dong M, Hu X, Ouyang W*, Peng J*, Zhang Z*. (2017) Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing. *Corresponding authors. Cell . 169(7):1342-1356.

Wong K, Noubade R, Manzanillo P, Ota N, Foreman O, Hackney JA, Friedman BA, Pappu R, Scearce-Levie K, Ouyang W. (2017) Mice deficient in NRROS show abnormal microglial development and neurological disorders. Nat Immunol . 18(6):633-641.

Basic Qualifications

PhD at the time of appointment

Preferred Qualifications

Ph.D. in immunology, oncology, bioinformatics or molecular biology

Independent research skills such as designing, executing and interpreting experiments, as demonstrated by previous publications

Experience in T cell biology, bioinformatics or immuno-oncology

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