Sr. Statistical Geneticist

Location
Tarrytown, NY, United States
Posted
Oct 24, 2020
Ref
22048BR
Required Education
Doctorate/PHD/MD
Position Type
Full time

Join our team and contribute to the analysis and interpretation of 100,000s of genotyped and sequenced humans, with the goal of generating the knowledge to enable Regeneron to deliver better medicines to the patients who need them. Work collaboratively with other experts in genomic data analysis, biology, computation and medicine to design, execute and refine analyses that connect genetic variation to human diseases and health and help develop and implement the methods and tools that will enable these analyses to be executed and interpreted at scale.

As a Sr. Statistical Geneticist, a typical day would may include:

  • Critically reviewing and providing input on analysis plans, results and summaries to ensure they are accurate and reliable.
  • Identifying potential problems and propose remedies or refinements.


To be considered for this role, you must have experience in the following:

  • PHD + 0-2+ years' relevant experience
  • Expertise with genome scale analyses with genotype or sequence data is critical. Demonstrated ability to execute and interpret analyses of genomewide association analysis, with sequencing or genotyping data as a substrate, is crucial.
  • Expertise in groundbreaking genomic analyses and their application to complex human traits is encouraged. The successful candidate will use cutting edge statistical genetic analysis methods to generate insights about human disease. Approaches that are currently being employed include genome-wide association analysis, exome-wide association analysis, rare variant analysis, Mendelian randomization, LD Score regression, polygenic risk score modelling, pleiotropy analysis, meta-analysis, and the use of functional data to prioritize variants and genes of interest.
  • Expertise with modern cluster and cloud computing environments is required. The candidate will routinely use advanced tools for genomic analyses (PLINK, SAIGE, samtools, Minimac, etc.) and for statistical analyses and computation (R, python, C/C++, Javascript) to execute analyses at scale.
  • Ability to work in a highly interactive environment with a diverse team of colleagues.
  • Outstanding communication skills and an ability to summarize and present the results of human genetic studies to a variety of technical audiences, ranging from specialists in statistical genetics and computation to specialists in biology, drug design, and medicine.


PREFERRED:

  • Experience conducting human genetic analyses of one of the following phenotype areas: cancer, vision disorders, eye disease, quantitative traits, drug response, cardiovascular disease, psychiatric disorders, neurological disorders, immune pathways, inflammatory diseases, hearing loss, infectious disease.
  • Experience conducting human genetic analyses in admixed populations, including genome-wide and local ancestry analysis.


Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accomodations you think you need.

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