Production Chemist I

Employer
Bachem
Location
Torrance, CA, US
Posted
Oct 22, 2020
Ref
515814101
Hotbed
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time
Your Responsibilities

The Chemist (Chem1) function is to develop the peptide manufacture process, manufacture GMP

material and perform related activities at Bachem.

Your Tasks

Perform synthesis process including solution phase and solid phase peptide synthesis, peptide resin cleavage, resin cleavage with HF or other chemical cocktails

Perform purification process by chromatography, crystallization and other techniques, and in-process test method

Follow approved GMP manufacture directions such as Master Batch Records, Standard Operation Procedures, Standard Test Procedures and other procedures to manufacture GMP materials, perform in-process test, package the product including other related activities

Perform project-planning and initiate raw material order-request. Receive raw materials, coordinate with QA/QC and Material Management for material release and monitor raw material inventories

Install, test equipment, operate and maintain equipment for manufacturing and in-process testing. The equipment includes analytical HPLC and prep HPLC system, Lyophilizes, balances, reactors, HF cleavage equipment, diafiltration systems, water purification systems, oven, washing systems and others used in manufacture

Develop processes for purification of chemicals other than peptides

Follow and maintain GMP Documentation System. Investigate any process deviation and write process deviation report. Initiate document change request. Help quality control and assurance unit to maintain equipment calibration program

Routinely maintain/organize work areas (Hood, bench, floor, wall, etc.) and other designated areas at the manufacturing facility

Develop peptide-manufacturing processes including peptide/protein purification by chromatography, crystallization, and other techniques, and in process test methods

Assist QA/QC for monitoring raw material inventories

Write Standard Operation Procedures, Standard Test Procedures, Master Batch Records and other related GMP documents

Follow SOPs and approved directions to clean equipment used in GMP processes, maintain cleaning log for each equipment, assist in equipment calibration program, and dispose chemical waste generated in the manufacture

Monitor compliance of Maintenance and Cleaning procedures of equipment and instruments used in GMP processes by periodically reviewing and signing off on maintenance and cleaning log for each equipment

Your Profile

BS degree in Chemistry or related field

1-3 years' work experience

Experience with HPLC and chromatography

May work with hazardous materials and chemicals

Excellent written and oral communication skills

Basic computer knowledge, including Microsoft Word, Excel and PowerPoint

Ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment

Ability to communicate in a proactive and solution-focused manner, including keeping management aware of potential issues.

Detail oriented with the ability to troubleshoot and resolve problems

Ability to work independently and manage one's time

Communicate effectively and ability to function well in a team environment

Flexibility of working hours based on business needs, may include some nights and occasional weekends

Preferred:

Experience with Peptides

General lab instrument (MS UV Spectrometry) knowledge and operation experience

Knowledge of cGMP and FDA regulations

We Offer

You will be part of a motivated team overseeing the entire development cycle of respective APIs. If you are

looking for a new challenge and want to join a motivated team in an internationally renowned company,

you should seize this opportunity.

Nearest Major Market: Los Angeles