Senior Research Scientist - Allogenic Process Development

Employer
Kite Pharma
Location
Santa Monica, CA, United States
Posted
Oct 22, 2020
Ref
R0015369
Required Education
Doctorate/PHD/MD
Position Type
Full time
Kite is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job

Job Description

Everyone at Kite is grounded by one common goal - curing cancer. Every single day, we seek to establish a direct line between that purpose and our day-to-day work. Would you like to join us in this mission?

We are seeking a highly motivated individual to join the allogeneic cell therapy Process Development team as a Senior Research Scientist - Allogenic Process Development. In this role, the successful candidate will support process development and technology transfer for Kite's engineered allogeneic T-cell therapy products, interact cross-functionally with partner functions to support pre-clinical and clinical development, as well as participate in new technology evaluation and implementation. The Senior Research Scientist will be expected to independently craft and perform experiments, coordinate and analyze results, and communicate findings through development reports and internal / external presentations.

Responsibilities of the Senior Research Scientist - Allogenic Process Development include:
  • Develop, optimize and establish allogeneic T-cell production platforms with a focus on T-cell isolation, enrichment, activation, and gene editing using viral and non-viral vectors
  • Design and execute studies to develop a thorough understanding of operating and performance parameters
  • Work on sophisticated problems where analysis of situations or data requires comprehensive evaluation of many factors
  • Develop and execute in process assays (e.g. flow cytometry) to understand attributes and phenotype of engineered T-cells
  • Participate in hands on activities that support process development and process characterization, ranging from drafting procedures to execution of laboratory studies, data analysis and authoring and review of technical documents
  • Routinely present results of work, including data interpretation and study conclusions
  • Maintain high level of expertise through familiarity with relevant scientific literature
  • Demonstrate effective communication and social skills to enable collaborative work
  • Cultivate reciprocal communication and problem-solving spirit


Requirements:

Ph.D. degree in cellular biology, virology, immunology or a closely related field with 3+ years of experience with flow cytometry, T-cell biology (e.g. phenotyping), and hands-on expertise with aseptic tissue culture of cell lines and/or primary cells OR a MS degree with 6+ years of the aforementioned experience OR a BS degree with 10+ years of the aforementioned experience.

Preferred Qualifications:
  • Experience with cell therapy, T-cell product generation, chimeric antigen receptor (CAR) based or TCR-engineered T-cells along with an understanding of T-cell and immune system biology
  • Ability to mentor and train more junior staff as a peer as well as a manager; together with the ability to work well within a matrix team environment
  • Demonstrated ability to critically design and execute experiments to support process development, characterization and process improvements
  • Knowledge of statistical design of experiments (DOE)
  • Strong organizational and record keeping skills
  • Excellent interpersonal, verbal and written communication skills are critical in this collaborative work environment
  • Demonstrated ability to function efficiently and independently in a fast-paced work environment and adjust workload based upon changing priorities


Does this sound like you? If so, please apply today!

#IND123

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.