Medical Director - Oncology (Solid Tumor)

Thousand Oaks, CA, US
Oct 22, 2020
Science/R&D, Oncology
Required Education
Position Type
Full time
Amgen is advancing the largest early Oncology pipeline in our history spanning several innovative technology platforms - Bispecific T Cell Engagers (BiTE®s), Cellular Therapies, Bispecific Antibodies, Small Molecules, and Oncolytic Viruses - across many targets and more than a dozen tumor types. We need collaborative and innovative world-class talent to ensure these molecules become medicines and reach their full potential while helping patients.

To support that effort, the Translational Medicine Group is looking for a Medical Director in Oncology.

The Medical Director will lead early phase clinical development of oncology compounds from first-in-human studies through proof of concept. They define, design, and execute early phase clinical and translational projects as the initial strategy for drug development. They typically serve as clinical project leaders for one or more of Amgen's Product Strategy Teams through their role as an Early Development Leader (EDL).

These experts represent Medical Sciences/Early Development internally and externally, contributing intellectual insight into experimental design and data analysis. They provide subject matter expertise in clinical and translational trial science as well as the biology and treatment of cancer.

  • Serve as an internal clinical expert in translational and clinical oncology.
  • Serve as medical monitor for clinical trials and assists in resolving major issues that may affect the studies.
  • Present information internally and externally, anticipating and proactively managing problems across a broad spectrum of cross-functional teams.
  • Coordinate clinical approaches to operational issues and assign monitoring and safety reporting resources.
  • Provide guidance and assistance in the identification and management of oncology phase 1 collaborators, consultants, and/or Clinical Research Organizations (CROs) in completion of key projects.
  • Ensure appropriate training, recruitment, and development requirements for matrix team resources.
  • Will be the primary Medical Sciences contact for basic scientists studying hematologic and solid tumor malignancies as well as for clinical research scientists overseeing later clinical development.
  • Evaluate external opportunities for partnering or licensing new oncology assets

Basic Qualifications

MD/DO degree from an accredited medical school


2 years of clinical research and/or basic science research experience

Preferred Qualifications
  • Subspecialty board eligibility/certification in Oncology and/or Hematology
  • Strong basic science or clinical research background in academia or industry
  • Prior experience authoring, monitoring, analyzing, and presenting oncology clinical trials
  • Effective presentation and communication abilities (both written and oral)
  • Ability to anticipate problems and find creative solutions
  • In-depth understanding of the scientific method and clinical applications based on medical, scientific and practical rationale including working knowledge of biomarker methods and clinical imaging endpoints
  • A record of high-quality peer-reviewed publications
  • Experience functioning as a medical expert in a complex matrixed environment
  • Previous experience in early phase development and/or biomarker work
  • Previous experience in late stage oncology clinical trials and regulatory filings
  • Demonstrated expertise in conducting translational and/or clinical oncology research
  • Expertise in Spotfire or other data analysis tools
  • Knowledge of GCP, EMA, and FDA policies
  • Expertise in authoring clinical sections of CTA or INDs

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.