Director, Inflammation, Biomarker Sciences

Location
Foster City, CA, US
Posted
Oct 20, 2020
Ref
2023661
Required Education
Doctorate/PHD/MD
Position Type
Full time
Director, Inflammation, Biomarker Sciences
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible


At Gilead, we strive to transform the promise of science and technology into therapies that have the power to cure, prevent or treat disease. As a research-based biopharmaceutical company, we are revolutionizing healthcare by bringing medicines to patients in the areas of HIV, AIDS, liver diseases, hematology and oncology, and inflammation and respiratory diseases.

We are growing a diverse team of professionals and an atmosphere of inclusion across departments. We need your unique talents, expertise and background to help millions of people around the world live healthier. Join a close community where every voice is heard - where you can see and measure the results of your contributions.

Our values - integrity, inclusion, teamwork, accountability and excellence - are evident in everything we do.

Director, Inflammation, Biomarker Sciences

The biomarkers group is seeking an experienced, exceptional scientist who will work in a dynamic, multidisciplinary matrixed team environment to generate and interpret data from translational and clinical studies. The successful candidate will be responsible for the development and execution of biomarker strategies for programs in the field of inflammation focused on the development of therapies for rheumatic diseases and inflammatory bowel disease. This individual will design experiments to advance biomarker discovery efforts to impact clinical development and the research pipeline. Experience in the analysis of multi-dimensional data sets and a strong understanding of mechanisms and immune pathways underlying inflammatory diseases is highly desirable.

Key Responsibilities:

This position will report to the Head of the Biomarker Sciences Inflammation Therapy Area

Direct the development, outsourcing, and validation of clinically applicable biomarker assays including pharmacodynamic, predictive, prognostic, safety and other biomarkers for inflammatory disease programs

Lead cross-functional Biomarker Teams to execute biomarker/diagnostic development strategies to generate, analyze, and interpret data from clinical studies

Identify, establish and oversee external collaborations with key opinion leaders, academic sites, and CROs to advance our understanding of disease pathways and prognostic/predictive biomarkers

Collaborate with Research Biology, Clinical Research, Bioinformatics and Biostatistics functions to create synergy in developing biomarker strategies and translational approaches

Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments in inflammation

Experience with genomic, epigenetic, gene expression, metabolomics, multiplexed protein detection or other related emerging platforms or data sets is desirable.

Must be able to work independently and effectively on multiple programs in a fast-paced matrixed environment

Excellent collaboration, communication, and interpersonal skills are required to engage and be productive within a high achieving team environment

Must be team and detail-oriented, motivated, and results focused.

Preferred Qualifications:
  • Demonstrated expertise in immunology or related field
  • Ability to integrate complex scientific ideas, generate testable hypotheses, and execute
  • Analysis and interpretation of biomarker data in preclinical and clinical setting
  • Experience with multi-dimensional data analysis is beneficial
  • Broad understanding of drug discovery and development in both early and late stage
    development and familiarity with regulatory approval process.
  • Knowledge of biomarker discovery and development, assay development/validation, clinical discovery of biomarkers, and MoA/translational research.
  • Authoring of biomarker strategy documents, biomarker specific portion of clinical protocols, and regulatory documents
  • Basic understanding of technical aspects of companion diagnostics development
  • Proven scientific/leadership expertise (working in teams, managing people/projects commensurate with level)
  • Proven publication record
  • Strong verbal and written communication skills
  • Understanding of IP, contracting terms and provisions


Requirements:
  • PhD and/or post-doc training in the area of inflammatory autoimmune diseases, immunology, or other related medical science field with a minimum of 12 years of relevant biotechnology or pharmaceutical industry experience.
  • Candidate must be detail-oriented with excellent record keeping and organizational skills.
  • Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic multi-disciplinary environment.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the ‘EEO is the Law' poster.

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Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

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To apply, visit https://gilead.wd1.myworkdayjobs.com/en-US/gileadcareers/job/United-States---California---Foster-City/Director--Biomarker_R0012458

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