Senior Research Associate, Pre-Clinical

Thank you for your interest in a career at Senti Biosciences. We are passionate about developing cell therapies with the ability to outsmart cancer and other complex diseases. We find purpose and meaning in knowing that our efforts will soon improve the lives of patients and their families. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.

Senti Bios is looking for a highly motivated candidate to join our Pre-Clinical In Vivo team and contribute to early stage oncology projects.

A successful applicant will be comfortable performing high risk/high impact research, work collaboratively across various projects to meet milestones, and play a key role in building the culture of the company as it grows. Applicants should have current knowledge of pre-clinical tumor models and animal handling and dosing.

Responsibilities

• Perform in vivo studies to evaluate efficacy in rodent models
• Proficient in the administration of test substances by various basic methods (i.e., IP, IV, SC, topical, etc.)
• Perform in vivo imaging to monitor tumor growth
• Manage and observe animals for general health and overall wellbeing
• Adhering to SOPs to ensure study integrity and quality
• Collaborate with research teams on relevant ex vivo assays (Flow cytometry, PCR, ELISA, IHC, etc.)
• Maintain accurate experiment records in various internal databases and perform basic data analysis
• Support scientific teams in multiple parallel projects
• Support lab and vivarium operation and maintenance
• Train research associates on the in vivo techniques and experiment workflow

Qualifications

• Bachelor's degree in life science or related discipline
• 3 years of experience in an animal laboratory setting
• Strong hands-on experience with animal handling, dosing (IP, IV and SC), necropsy, and tissue harvest. Experience with or willingness to learn animal bleeding techniques is a plus
• Experience with tumor implantation and tumor measuring is a plus
• Experience with data analysis software, Prism is a plus
• The ability to independently perform all methods and conduct all study types commonly employed by the team
• Good organizational and documentation skills
• Dedication to working in a team-oriented environment to contribute to shared project
• Strong work ethic, self-motivation, and ability to multi-task in a fast-paced work environment
• Excellent communication skills with ability to effectively communicate with other research teams

Salary and Benefits

• Competitive compensation package and title commensurate with qualifications and experience in the South San Francisco Biotech market.
• Significant growth opportunity as the company expands.

Senti Bio is the next generation therapeutics company that designs gene circuits and programs cells for tremendous therapeutic value. Our mission is to engineer an entirely new class of medicine that will transform people's lives by curing the most challenging diseases. We are proud to count NEA, 8VC, Amgen Ventures, Pear Ventures, Lux Capital, Menlo Ventures, Allen & Company, Nest.Bio , Omega Funds, Goodman Capital, and LifeForce Capital among their investors. Senti Bio is based in South San Francisco, CA, USA.