Intern, Platform Development

Location
San Diego, CA, US
Posted
Oct 15, 2020
Ref
5694
Hotbed
Biotech Beach
Required Education
Bachelors Degree
Position Type
Full time
Overview

Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological genetic diseases? Since 2013, Novartis Gene Therapies (formerly AveXis) has had one focus: bringing change to those devastated by genetic diseases.

The Novartis Gene Therapies culture embraces this mission. As a compassionate and dedicated team, we are enthusiastic about the science behind our work and finding answers to difficult questions. We are dedicated to communities affected by rare diseases, and these patients and families are the motivation for everything we do.

We have built a team with exceptional depth of experience, unified by a common vision; to develop gene therapies with the potential to positively impact the lives of the patients and families devastated by rare and life-threatening neurological genetic diseases. Though we are proud of what we have achieved to date, we remain relentlessly focused on making that vision a reality.

Novartis Gene Therapies (GTx) platform development group is seeking a motivated intern to contribute to implementation of novel advances in the gene therapy field to enable safe and efficacious treatment strategies. The ideal candidate a will be a student currently enrolled in an accredited undergraduate, master's or doctoral program majoring in a relevant scientific field, with experience in areas such as cell and molecular biology, genomics, rodent studies and/or tissue handling and processing for biochemical and molecular characterization. The role will give the chosen candidate an opportunity to learn about the biotechnology industry in a hands-on manner, to pursue an exciting summer gene therapy project and to interact with our leaders, experts and colleagues in Novartis research centers across the world.

Responsibilities
  • Assist with the establishment and optimization of assays and to characterize treatment efficacy and safety in target/nontarget cells from cell-based and animal studies.
  • Learn cutting edge virology, immunology, cell and molecular biology methods, AAV vector design and production.
  • Expand knowledge regarding rare disease research and considerations for target prioritization and validation.
  • Under supervision, maintain immortalized/primary/iPS cell culture, conduct hands-on laboratory work with AAVs.

Qualifications
  • Current enrollment in an accredited undergraduate, master's or doctoral program, majoring in biology, virology, immunology, neuroscience, bioengineering cell/molecular biology, or related scientific discipline.
  • Experience with cell/molecular biology with techniques including PCR, RT-qPCR, ddPCR analysis, microscopy, ELISA/MSD/ Western-Blot, cell culture, transfection, or viral transduction are desired.
  • Candidates with experience in gene therapy, NGS, genomics, and immunology are preferred.
  • A willingness to learn and contribute to GTx's mission and goals
  • Attention to detail
  • Excellent oral/written communication and interpersonal skills.


The level of this position will be based on the final candidate's qualifications.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

Novartis Gene Therapies is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status.

#LI-EC1