Senior Scientist

Gaithersburg, MD, US
Oct 15, 2020
Required Education
Bachelors Degree
Position Type
Full time
Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and growth opportunities. Here, you will join passionate professionals who advance their scientific, technical and professional skills to develop products designed-to protect life.

Job Summary

The Senior Scientist position is involved in the development, optimization and tech transfer of Downstream purification processes for recombinant protein, mAb and virus based vaccines.

Essential Functions

Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions.

• Execution of experimental protocols for developing/optimizing manufacturing processes
• Development of scalable, production processes for cell culture and fermentation producing recombinant proteins and recombinant viruses.
• Identifying appropriate equipment and process scale and technology transfer to manufacturing for candidate proteins to be used as vaccines and/or therapeutics.
• Trouble shooting and maintenance of cell culture and fermentation systems
• Develop Harvest, Clarification and Recovery processes utilizing standard methods including centrifugation and multiple forms of filtration.
• Preparation of experimental protocols, Operational and Maintenance Equipment SOPs and Manufacturing Batch Records.
• Review of documentation such as Technology Development Reports, Technology Transfer Protocols,
• Train other members of the development services and manufacturing team in cell culture and microbial fermentation techniques.

The above statements are intended to describe the general nature of work performed by those in this job. It is not an exhaustive list of all duties, and other duties may be assigned.

Minimum Education, Experience, Skills

• Ph.D. or MS degree in biology, biochemistry, engineering required. 5 plus years of related experience with Ph.D. and 10 years with Masters; includes post-doctoral experience or BS with 13-15 years' experience depending on area of responsibility.
• Extensive knowledge of bioprocess unit operations specifically protein biochemistry and protein purification required.
• Hands on experience using cell culture and fermentation production equipment including cell stack and roller bottles, AMBR microreactors, iCELLs reactors, standard 1 to 10 L reactors like the Sartorious series, and GE SUBs, as well as centrifugation and various filtration systems.
• Matrix based experimental design is required and experience with DOE highly desirable.
• Knowledge and/or experience with upstream fermentation/recovery are also important. Understanding of Design of Experiments and knowledge of JMP software

Emergent BioSolutions is an Equal Opportunity/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, Protected Veteran status, sexual orientation, or any other characteristic protected by federal, state or local law.

Information submitted will be used by Emergent BioSolutions for activities related to your prospective employment. Emergent BioSolutions respects your privacy and any use of the information submitted will be subject to the terms of our Privacy Policy .

Emergent BioSolutions does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on Emergent BioSolutions' approved agency list. Unsolicited resumes or candidate information submitted to Emergent BioSolutions by search/recruiting agencies not already on Emergent BioSolutions' approved agency list shall become the property of Emergent BioSolutions and if the candidate is subsequently hired by Emergent BioSolutions, Emergent BioSolutions shall not owe any fee to the submitting agency.