Senior Research Associate - Process Development

Employer
PACT Pharma
Location
94080, South San Francisco
Salary
Salary + Benefits + Pre IPO Equity
Posted
Oct 14, 2020
Ref
2020133
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time

PACT Pharma is an exciting, well-funded clinical-stage company developing personalized adoptive T cell therapies for the eradication of solid tumors. Our private designer T cells are created by analyzing a patient’s individual tumor and engineering T cells to kill that specific tumor. 

If you desire a stimulating fast-paced environment, working with intelligent people who are making an impact in cancer, you will want to join the PACT Pharma team.  We are a rapidly expanding, innovative, and collaborative workforce working towards one main goal, eradicating cancer! 

We are in the San Francisco bay area, the heart of the world’s premier biotechnology research hub. PACT Pharma offers a competitive compensation and benefits package, including participation in the aggressive growth of the company in the form of stock option grants. 

We are currently recruiting for a Sr. Research Associate in our Process Development department who will report to the Sr. Director, Plasmid Manufacturing and continue advancing PACT’s cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives. 

The person in this role will be responsible for performing experiments for continuous optimization of PACT’s manufacturing process focused on delivering plasmids for gene editing. He/she will interact closely with scientists and other research associates to evaluate potential process improvements and transfer the technology from small scale research to large scale processes. The ideal candidate will have experience in large scale plasmid preparation and automation. She/he will be actively performing experiments and should be highly proficient in state-of-the-art techniques for bacterial fermentation and chromatography.  The candidate should enjoy operating in an exceptionally dynamic and cooperative environment.

Responsibilities:

  • Perform small-scale and large-scale process development experiments using bacterial transformation and selection, fermentation, plasmid purification, formulation, and cryopreservation methods  
  • Analyzing data and writing reports

Minimum Qualifications:

  • The ideal candidate should hold a bachelor’s degree with 4+ years’ experience, or hold a master’s degree with 2+ year experience
  • Must have experience in bacterial fermentation techniques and plasmid purification.
  • Experience with chromatography and automation is preferred
  • The candidate should be well-organized, GMP or GMPI-like laboratory experience a plus
  • TFF (tangential flow filtration) experience is a plus
  • The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives. 

PACT Pharma is proud to be an equal opportunity employer and strives to build a diverse and inclusive team. We do not discriminate on the basis of race, color, national origin, religion, gender, sexual orientation, age, marital status, veteran status, or disability status.