Sr. Scientist, Formulation

Employer
Arranta Bio
Location
Gainesville, FL, United States
Posted
Oct 14, 2020
Ref
85503-309839
Required Education
Doctorate/PHD/MD
Position Type
Full time
ABOUT US

Arranta Bio is a rapidly growing and dynamic bio-pharmaceutical contract development and manufacturing organization (CDMO). Our vision is to be the best in class CDMO providing development and GMP manufacturing services to microbiome innovators within the pharmaceutical industry. Therapies focused on the human microbiome are exhibiting incredible potential towards revolutionizing disease etiology and associated medical treatments. Arranta Bio's mission is to build a world class organization which provides microbiome bio-pharmaceutical innovators with a single source of supply from early process development through clinical and commercial GMP finished product.

WHO ARE WE

Arranta hires people who are committed and passionate to the goal of bringing life enhancing products to patients. We want top talent who will render ideas and a relentless desire towards accomplishing our mission; when a job becomes a passion, it makes you feel ALIVE.

Here at Arranta Bio, we embrace ALIVE - our core values that we live and breathe daily! We are Agile, Leading, Innovating, Value Creating, and Engaging.

We embrace our challenges as opportunities.

We are empowered to think and act.

We never settle; we strive to improve through purposeful creativity.

We build aligned teams who learn, grow, and deliver.

We are committed to building strong relationships.

Are you ready to come ALIVE with a daring and intrepid team? Don't wait another minute; Apply today!

JOB SUMMARY

The candidate will join a team of Scientist's responsible for the development and manufacturing of solid oral dose formulations as well as other drug product format formulations (as needed) and analytical assays for LBP production processes to work within our state-of-the-art process development and manufacturing laboratories. To be successful in this role, will require collaboration with other departments and external collaborators to support new programs. Candidate must be innovative and possess exceptional analytical and communication skills.

ESSENTIAL RESPONSIBILITIES
  • Plan and execute experiments to support microbial formulation and drug product development
  • Create process development plans
  • Independently generate list of material required for experiments
  • Independently analyze experimental data
  • Create presentations on generated data and present to team
  • Serve as subject matter expert for formulation development, product formats and Drug Product manufacturing
  • Manage budget, milestone and timeline
  • Engage with internal teams and external collaborators
  • Communicate openly across other functions and departments
  • Build and maintain collaborative relationship with other department and external customers
  • Be a technical expert on formulation development and Drug Product development processes
  • Present findings and or results to senior management
  • Upstream activities including sieving, blending, flowability/compatibility evaluation
  • Downstream activities including encapsulation (banding, coating, polishing etc), sachet, bead development, bottling, blistering etc
  • Analytical activities including assays using disintegration/dissolution, karl fisher, water activity, HPLC, plate reader, fluorescence microscope etc
  • Setup and operation of drug product processing equipment and systems
  • Application of DOE methods for process optimization
  • Writing SOPs, protocols and reports
  • Aid in tech transfer
  • Cultivate a continuous improvement & right-first-time mindset underpinned by strong ownership and accountability
  • Author batch records and process descriptions


Experience and Skills

EDUCATION AND/ OR EXPERIENCE
  • PhD with 8+ years of relevant industry experience
  • BS or MS in chemical engineering, biotechnology, or microbiology, with 10+ years of relevant industry experience
  • A strong understanding of formulation and experience with development of drug product processes
  • A strong understanding of oral solid dose development and manufacturing is highly desirable
  • Ability to resolve difficult scientific challenges with innovative novel ideas is essential
  • Knowledge of current Good Manufacturing Practices is a plus
  • Strong verbal and written communication skills are integral to this position
  • Excellent attention to detail and able to work methodically
  • Good teamwork and ability to work effectively with others
  • Good grasp of written English
  • Good grasp of mathematical principles
  • Experience working with aseptic technique
  • Previous experience in process development
  • Experience with upstream, downstream processing and analytical methods a plus


PHYSICAL DEMANDS
  • A flexible work schedule is required.
  • Ability to lift up to 25 lbs.