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Scientist / Senior Research Associate, In Vivo Pharmacology

Employer
Maze Therapeutics
Location
South San Francisco, CA, United States
Start date
Oct 7, 2020

View more

Discipline
Science/R&D, Biotechnology, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay, NextGen Bio

Job Details

We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly-growing startup on our mission to translate novel genetic insights into lifesaving medicines. We are integrating human genetics and functional genomics to decode the mysteries of genetic modifiers, leading us to new medicines we'll develop for a range of severe diseases.

We are seeking qualified in vivo pharmacologists with experience in preclinical pharmacodynamic and disease models. Applicants must feel comfortable with the fast pace of a small biotech company and have the flexibility to work on multiple projects. You will collaborate with biologists and drug discovery scientists to develop innovative vivo models and execute studies.

Your Role in Navigating the Maze:
  • Conduct in vivo preclinical studies to demonstrate target engagement or efficacy in
    disease models to support drug candidate discovery
  • Assist in model development
  • Manage, process, analyze and present data
  • Assist with the coordination of studies with CROs
  • Collaborate with project teams on preclinical studies

Your Navigation Tools:
  • BA/BS/MS in relevant field with 3+ years' experience in pharmacology or related
    discipline within a pharmaceutical company
  • Broad expertise with in vivo preclinical pharmacodynamic or disease models
  • Experience with in vivo biological sample collection for pharmacokinetic analysis
  • Fluency with general biology lab procedures
  • Solid knowledge of pharmacology concepts
  • Excellent communication skills and ability to work in a team-based environment
  • Detail oriented and highly organized
  • Experience representing Pharmacology in cross-functional project teams

Company

Maze Therapeutics is translating novel genetic insights into lifesaving medicines, through an approach that integrates human genetics and functional genomics. Advances in these areas have enabled us to decode the mysteries of genetic modifiers in a range of severe diseases, which we aim to turn into medicines that mimic protective mutations. 
 
What are genetic modifiers?
 
Despite an understanding of the genetic basis for many diseases, it remains a mystery why some people with a disease-causing mutation never get sick. This is often due to genes elsewhere in our DNA that affect the severity of disease and can provide a natural form of protection.
 
The Maze approach
 
Dramatic advances in human genetics and functional genomics now enable us to decode the mysteries of genetic modifiers in a range of severe diseases. Today, we believe we can systematically identify genetic modifiers and turn these insights into medicines. We have assembled a world-class team to realize this vision, including creative scientific pioneers, experienced company builders and biotech industry leaders.
 
Join us in our pursuit to change lives by translating genetic insights into medicine - view our job postings with the link to the left.

Company info
Website
Location
171 Oyster Point Blvd, Suite 200
South San Francisco
CA
94080
United States

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