*Biological Research Associate II

Irvine, CA, United States
Oct 06, 2020
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Job Description

Envision working with energetic colleagues and inspirational leaders. Now, place yourself in that mix; leading discussions, asking the right questions and driving results. AbbVie is always striving to find top scientists to work at our Irvine, CA site

Scientific Associate II - Protein Science- Irvine, CA

What your manager wants you to know:

I'm looking for a team player to contribute to a dynamic and highly matrixed Discovery organization. If you are interested in applying your protein purification and characterization skills to the discovery and creation of novel protein-based therapeutics, I would be very interested in receiving your resume. Let's discuss what you can bring to the team and what you aspire to do in the future."

Successful Scientific Associates will contribute by: contributing their expertise to projects aimed at purifying and characterizing protein-based therapeutics. He/she will develop and carry out a variety of protein purification strategies including affinity (IMAC) and tagless purification (IEX,SEC, HIC) from bacterial expression systems utilizing AKTA systems. Additional protein research will include analysis by SDS-PAGE, Western blot, ELISA, HPLC (reverse phase/size exclusion), protease assays, thermal stability, light scattering to evaluate the activity and functionality of therapeutic proteins. This individual will organize, analyze and interpret results, come forward with recommendations or understanding of the results, and communicate and present in team meetings and reports. The ideal candidate will be able to propose and design assays and have exceptional troubleshooting skills.


Be a trusted and expert scientific partner.
  • Independently conduct experiments of moderate complexity, designing the work plan so that reliable results are achieved in a timely manner.
  • Plan experimental approaches with supervisory guidance. Discuss, recommend, and modify experimental techniques as needed.
  • Document and interpret results in order to reach conclusions, discuss with supervisor and decide on subsequent experiments.
  • Management of laboratory supplies and equipment needed for research (ordering supplies, equipment maintenance, record keeping, and inventory).
  • Develop and maintain up-to-date knowledge and skill base by reviewing the literature, attending seminars and meetings.
  • Prepare technical reports, presentations, and appropriate documentation of work performed. Assist supervisor in maintaining project documentation.
  • Attend and participate in lab, team and departmental meetings. Present data as required.


  • Experience with protein/enzyme characterization including SDS-PAGE, western bots, DLS/aggregation, HPLC (reverse phase/ size exclusion) and enzyme assays is desirable.
  • Bachelor's degree in Chemistry, Biology, or related life science field and 1 - 3 years relevant experience in protein purification and characterization

  • Excellence Focused
  • Open and Authentic


Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.