Associate Scientist II / Scientist I - In Vivo Antibody Discovery

Worcester, MA, United States
Oct 05, 2020
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie Global Biologics and Virology Research is an integrated, global discovery organization responsible for anti-viral drug research across indications including HIV AIDS, Hepatitis C, and emerging viral syndromes. Our scope includes the discovery of innovative small molecule and biologic medicines from the early exploratory stage and their support through clinical development. We are growing a world-class team of scientists and leaders who will drive the discovery and advancement of innovative anti-viral and biologic-based therapies. Careers in AbbVie Global Biologics and Virology provide unique opportunities to work with cross-functional teams that drive exceptional science and deliver innovative medicines to patients. We are looking for diverse candidates with strong scientific and leadership experience to join the team and can offer exciting and rewarding career opportunities for these candidates.

The Biologics Generation Group within Global Biologics is seeking a highly motivated Research Scientist to join the In Vivo Antibody Discovery team at the AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers the unique setting where Biologics drug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative immunization approaches, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets.

As an integral part of the group, the ideal candidate will:

  • Exercise proficiencies in mammalian tissue culture, molecular techniques, and binding assays such as ELISA and flow cytometry
  • Execute all phases of in vivo antibody discovery campaigns by hybridoma generation or single cell isolation including immunizations, screening, cell culture and antibody characterization
  • Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment
  • Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas


Position will be hired based on knowledge and/or level of experience.

  • BS or MS in Biology or other related field with 0-5+ years (BS), or 0-3 years (MS) of industry or academic experience
  • Knowledge of basic immunology concepts
  • Experience with aseptic mammalian cell culture technique
  • Understanding of immunoassays (e.g. flow cytometry and ELISA)
  • Strong attention to quality and details when exercising organizational, documentation and communication skills
  • Proven flexibility to deal with changing timelines and shifting work priorities
  • Competency with software programs, including MS Excel, PowerPoint, Word


  • Experience in immunoassays using techniques like flow cytometry, ELISA and microscopy
  • Animal handling experience (e.g. restraint, immunizations, tissue harvesting etc.)
  • Familiarity with microfluidics and single cell analysis platforms

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Yes, 5 % of the Time
Job Type
Job Level Code
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.