AbbVie

Principle Research Scientist II, Oncology, Precision Medicine

Employer
AbbVie
Location
Lake County, IL, United States
Posted
Oct 03, 2020
Ref
2004899
Required Education
Doctorate/PHD/MD
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Overview:

The Translational Oncology of Precision Medicine department at Abbvie uses advanced methods to discover biomarkers and implement translational medicine strategies to progress Abbvie's innovative Oncology pipeline. We are currently seeking a highly motivated and independent individual to join our team as a Principle Research Scientist II to lead and oversee development and execution of Precision Medicine strategy for Abbvie sponsored or collaborative clinical trials . As a member of both research and clinical development project teams he/she will have the opportunity to work in a highly collaborative environment to support projects across all phases of clinical development.

The key responsibilities will be:
  • As Precision Medicine Team Leader, responsible for independently developing and executing the overall Precision Medicine Strategy for one or more Oncology compounds
  • Serves as a point of contact for all aspects of Precision medicine strategy providing scientific expertise and leadership to programs
  • Enables cross functional collaboration on precision medicine strategy implementation. Leads the design, execution, analysis, communication, and publication of translational research and correlative clinical biomarker studies
  • Responsible for Precision Medicine related sections in clinical study / regulatory documents (i.e. INDs, IBs, trial protocols/ops manuals, ICFs, IRB responses, HA Briefing Books, CSRs, etc)
  • Provides oversight of external collaborations (academic/industry/ consortia) that advance Precision Medicine objectives for the program
  • Represents Precision Medicine function at ad boards and health authority interactions to advance translational research and clinical biomarker objectives for the program
  • Apply multiple genomic and biochemical technology platforms to demonstrate target engagement, develop patient selection/CDx strategies (in partnership with CDx group).
  • Implement potential novel bioanalytical platforms and introduce new ways to incorporate biomarkers into clinical program designs.
  • Design and perform experiments to elucidate resistance mechanisms that can be developed into novel targets for new therapeutics.
  • Function as an internal expert in oncology biomarkers and precision medicine and actively educate other team members through knowledge sharing.
  • Present and report data in external meetings and publications.

Qualifications

Qualifications

  • M.D. and/or Ph.D. in Cancer Biology, Cell Biology, Molecular Biology or related field with 8+ years of post-doctoral experience
  • Experience in independently leading matrixed clinical biomarker team, and developing/implementing translational medicine strategies for one or more Oncology programs in industry setting is a must
  • Strong scientific background in tumor biology and expertise in immuno-oncology, epigenetics, or tumor immune microenvironment is preferred.
  • Demonstrated technical excellence and expertise in Translational medicine; including hands-on experience taking small molecules and/or biologics through clinical development. Experience in analysis of large datasets and knowledge of biostatistics will be useful.
  • Experience in the utilization of various technologies/platforms ( -omics technologies , immunohistochemistry and immunoassays, etc.) for biomarker research.
  • Effectively work in a cross-functional team environment, interacting with various levels within the organization as well as vendors/academic sites/KOLs
  • Excellent interpersonal and communication skills.


  • Must be able to work effectively on multiple oncology programs in a fast dynamic environment.


Key AbbVie Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.


Significant Work Activities
Keyboard use (greater or equal to 50% of the workday)
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
Yes, 5 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.