Principal Scientist/Associate Director, Bioinformatics/Computational Biology 资深科学家/副总监

Location
San Francisco, CA, United States
Posted
Oct 02, 2020
Ref
193471653
Hotbed
Biotech Bay
Required Education
Doctorate/PHD/MD
Position Type
Full time

Primary Function:

We are seeking an innovative computational biologist to drive Zai Laboratory's bioinformatic efforts from early drug discovery through late stage development. The successful candidate will apply machine learning, network analysis, and other cutting-edge bioinformatic methodologies and leverage large, multi-omic datasets to identify new targets, develop patient stratification strategies, and help guide the development of Zai's clinical pipeline.


Major Responsibilities and Duties:

- Lead computational efforts on multi-disciplinary teams, and apply cutting-edge computational approaches to gain maximum insights from large, multi-omic pre-clinical, clinical, and real-world datasets

- Collaborate with cancer biologists, immunologists, chemists, statisticians, and develop computational strategies and build tools for target discovery, patient stratification, and development of pharmacodynamic and predictive genomic signatures

- Effectively communicate findings at internal and external meetings

Qualifications:

- Ph.D. in computational biology, engineering, statistics, cancer biology, immunology, genetics, or similar field, with 5+ years of experience

- Extensive expertise in programming using languages such as R or Python and analysis of multi-dimensional genomic and/or proteomic datasets, particularly transcriptome-wide data from pre-clinical, and ideally, clinical samples

- Strong track record of systematically evaluating and prioritizing multiple hypotheses using bioinformatic approaches both independently and collaborativel

- Excellent problem-solving and collaboration skills

- Strong communication, data presentation, and visualization skills

- A strong background in oncology and/or immuno-oncology is highly desired