Associate Director/Director of Chemistry - Genesis Therapeutics

Location
San Diego, CA
Salary
Competitive
Posted
Sep 28, 2020
Required Education
Doctorate/PHD/MD
Position Type
Full time

Associate Director/Director of Chemistry - Genesis Therapeutics

As an Associate Director/Director, Medicinal Chemistry at Genesis Therapeutics, your expertise will play a significant role in designing new molecular entities to help transform patients' lives. Working in conjunction with company leadership and software engineers, you will have management responsibilities and direct oversight of both internal and external activities to leverage cutting edge artificial intelligence, medicinal chemistry and drug discovery experience in the pursuit of safe and effective medications.

RESPONSIBILITIES - Essential duties and responsibilities include the following.

  • Responsible for oversight, leadership, and implementation of drug discovery programs/initiatives.
  • The design of novel small molecule drug candidates for in vitro/in vivo biological studies with the goal of providing proprietary clinical candidates.
  • Manage CRO activities and contractual relationships .
  • A deep understanding of ADME properties and pharmacological data in the design of novel small molecule drugs.
  • Design synthetic routes to novel molecules and execute their timely implementation.
  • Preparation of patent applications.
  • Regular project presentations to management, scientific advisory board and other stakeholders.
  • Assist in the establishment of new lab facilities

EXPERIENCE - Minimum Requirements:

  • Ph.D. in Synthetic Organic or Medicinal Chemistry with at least 10+ years of industrial experience in Drug Discovery & Development. 
  • Verifiable track record of drug discovery experience, success and leadership, with experience in advancing compounds through all stages of discovery to delivery candidates. 
  • Extensive publications in peer-reviewed journals and the patent literature are a plus.
  • Strong written and interpersonal communication skills.
  • Management experience directing the activities of a chemistry team.
  • Experience with structure-based drug design tools.

About Genesis Therapeutics

Genesis is pairing proven drug developers with the industry’s most advanced AI platform for small molecule discovery. Genesis originated in deep learning research at a top AI lab at Stanford and has since been joined by some of the world's most accomplished drug discovery & development scientists and biotech entrepreneurs. We have already validated our tech in big pharma and have raised seed funding from Andreessen Horowitz and other top investors. Recently, we were featured in the Forbes AI 50. Leveraging bleeding edge artificial intelligence written from the ground up to more comprehensively represent the interaction of molecules with proteins and their conformational flexibility, we accelerate the drug discovery process through more informed decision making and insight. We are currently recruiting top medicinal chemists, biologists, and AI engineers as we aim to transform the lives of patients suffering from severe and unmet medical conditions.