Senior Process Engineer - Team Lead - Cell Therapy

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS's continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

Come and join Bristol Myers Squibb for this key role helping to build a leading CAR T Platform that serves our patients with novel CAR T Therapies. At BMS, we are developing novel cellular immunotherapies based on two distinct and complementary platforms - Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body's immune system to treat cancer.

The Senior Engineer in this role will lead a team of engineers in the Global Manufacturing Sciences and Technology Lab in Seattle. The team is responsible for executing late-stage, business-critical activities related to liquid raw materials, buffer and reagent formulation improvements for commercialization and post-commercial support of cell therapy processes.

Major job duties include:

• Direct management of 3-4 engineers; providing technical leadership for experimental design, execution, data interpretation and report writing.
• Support the late-stage development of liquid raw material improvements including, container closure, automated formulation, sterile filtration and second sourcing to meet business needs and manufacturing requirements
• Provide scientific leadership on technical teams for raw material changes and improvements
• Leadership/mentorship for direct reports to support business goals and career development
• Collaborate with Manufacturing, other GMS&T functions, and technical development groups to achieve GMP process solutions
• Provide technical content for significant documents such as PPQ or comparability assessments, author content for regulatory submissions

Basic Qualifications:

• PhD in Biological Science, Biomedical Engineering, Chemical Engineering, or related discipline with 4 years development / manufacturing technologies experience, MS with 6 years or BS with 8 ormore years development / manufacturing technologies in pharmaceutical industry
• Strong understanding of bioprocess unit operations, especially cell culture.
• Extensive knowledge of regulations, current industry practices, and experience with interpretation and application of guidelines and regulations
• A strong mindset for high-quality, meticulous, and consistent execution of manufacturing processes and/or analytics
• Excellent written and verbal communication skills. Ability to convey complex technical issues to diverse audiences including internal teams, external partners, and health authorities.
• Strong interpersonal skills to work across multiple stakeholders and customers
• Sound experience of data handling and applied statistics

Preferred Qualifications:

• 2-3 years of experience in cell therapy technical operations
• Experience developing and implementing sterilizing grade filtration
• 2 years of direct management experience
• Experience with commercial product support, i.e. post-marketing commitments, life-cycle changes, comparability

If you want to challenge yourself, accelerate your career, and give new hope to patients, there's no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients' lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.

BMSCART

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.