Scientist, Cell Therapy Immunological Assay Development

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

We are recruiting a scientist to join the Custom Process Analytics (CPA) team of our Cell Therapy Analytical Development (CTAD) organization in Warren, NJ. The ideal candidate will work with a talented and experienced team to enable the rapid advancement of cellular therapy products from pre-clinical development through commercialization.

The ideal candidate will have experience in the development and implementation of analytical methods for cell therapy product characterization, including flow cytometry, cell based functional assays, molecular biology, and implementation of method automation and new technologies. The incumbent will provide custom method development and sample testing in support of cell therapy manufacturing process development and drug product characterization activities. This position will report into the head of CPA.

Responsibilities will include, but are not limited to:

• Serve as a subject matter expert for flow cytometry, cell-based function (e.g. signal transduction, cell killing), molecular (qPCR), and/or protein quantitation (Luminex, MSD, ELISA) analytical methods.
• Develop and implement methodologies to characterize genetically engineered cells (e.g. CRIPSR/Cas modified), to ensure successful engineering.
• Lead and coordinate sample testing activities in support of manufacturing process development studies and drug product characterization. This includes; sample management, test scheduling, and method support.
• Ensure robust data acquisition, analysis, integrity, and reporting in an efficient and timely manner.
• Collaborate with other departments within the larger Product & Analytical Development (P&AD) organization.
• Provide scientific guidance to development operations, clinical, and commercial QC teams. Maintain current awareness of GMP/GTP and other regulations, guidance documents, advisory committees, industry standards and trends that are applicable to current and future Cell Therapy Development operations and products.
• Communicate effectively to staff, key partners, and stakeholders in a rapid and efficient manner.

Skills/Knowledge Required:

• PhD in cell biology, immunology, molecular biology, or related discipline with 0-3 years R&D / analytical development experience, or MS with 6+ years R&D / analytical development experience in a relevant field.
• Extensive technical experience in flow cytometry and/or molecular biology methodologies.
• Experience designing cell-based functional assays is strongly preferred.
• Experience with CRISPR/Cas genome editing is preferred.
• Experience with high-volume and rapid sample testing is preferred.
• Familiarity with and constant attention to the evolving cell therapy landscape through literature review/publication, conference attendance, industry working group leadership, etc.
• Strategic thinker with excellent problem solving and conflict resolution skills.
• Ability to foster a strong team-first environment with the ability to lead multiple projects.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.