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Research Associate III, MoCha Clinical Lab Manager

Employer
Frederick National Laboratory for Cancer Research
Location
Frederick, MD, USA
Start date
Sep 24, 2020

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Discipline
Clinical, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
BioCapital

Job Details

The Molecular Characterization Laboratory (MoCha) is part of Leidos Biomedical Research's Clinical Research Directorate (CRD) at the Frederick National Laboratory for Cancer Research. The MoCha Laboratory is responsible for providing high-level research in support of the NCI-Cancer Diagnostics Program (CDP) within the Division of Cancer Treatment and Diagnosis (DCTD). MoCha is charged with the development and application of genomic assays for use in medical research and diagnostics for DCTD-sponsored national extramural clinical trials.

KEY ROLES/RESPONSIBILITIES

The Research Associate III will serve as the CLIA Laboratory Manager, and technical lead responsible for facilitating cutting edge genomic research in support of DCTD projects, including NCI MATCH, NCI Pediatric MATCH, and upcoming NCI precision medicine initiatives under MdNet.
  • Manage scientific staff in the development and optimization of new assays and technologies, leveraging genomics and NGS platforms available at MoCha
  • Perform quality control and troubleshooting activities independently and in consultation with MoCha senior scientific staff
  • Recommend and optimize new NGS assay platforms
  • Perform analytical validation of genomic and NGS assays
  • Develop and maintain SOPs for above-mentioned research activities and projects
  • Perform formal reporting of research data including oral presentations to senior staff, abstracts for scientific meetings, and manuscript preparation for scientific journals
  • Maintain knowledge of the most recent literature and scientific presentations relevant to ongoing projects
  • Supervise CLIA technicians and ensure CLIA standards are maintained
  • This position will be located in Frederick, Maryland.

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
  • Possession of a Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA). Additional qualifying experience may be substituted for the required education
  • Foreign degrees must be evaluated for U.S. equivalency
  • In addition to educational requirements, a minimum of eight (8) years of relevant experience
  • Strong technical skills in molecular assays and/or nucleic acid extraction and a thorough understanding of QC metrics for nucleic acid testing
  • Extensive experience working in a CLIA environment and be knowledgeable in all aspects of maintaining a laboratory according to CLIA standards
  • Ability to independently evaluate the suitability and quality control of research or production assays or tests, develop and follow SOPs, and analyze and report data
  • Ability to track information in a large cohort of samples and monitor progress of multiple projects
  • Adequate computer skills to document, organize, and present experimental data
  • Strong critical thinking and problem solving skills
  • Ability to communicate effectively, both verbally and in writing
  • Must be able to obtain and maintain a Security Clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:
  • Masters degree in a relevant field of study
  • Extensive experience in genomic and next generation sequencing (NGS) assay development
  • Experience in NGS assay troubleshooting
  • Experience in NGS assay validation and harmonization
  • Familiarity with clinical oncology studies and other protocol-driven clinical research

EXPECTED COMPETENCIES
  • Strong understanding of molecular biology techniques used in genomic research
  • General familiarity with cancer biology and clinical research
  • Excellent communication skills (written and oral)
  • Ability to work effectively in a matrix and team‐oriented environment
  • Ability to identify and solve complex problems
  • Strong organizational and multitasking skills

JOB HAZARDS
  • This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s)
  • This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations


Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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Company

A rewarding career with global impact

Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.

Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.

We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.

Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.

Discover why joining the Frederick National Laboratory team could be the most important career step you take

 

 

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Company info
Website
Phone
301-846-1000
Location
8560 Progress Drive
Frederick
MD
21701
US

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