Sr. R&D Specialist (Autoimmunity)

Tarrytown, NY, United States
Sep 23, 2020
Required Education
Masters Degree/MBA
Position Type
Full time
The Immunology & Inflammation department is seeking a Senior R&D Specialist to focus on evaluating novel immune modulation mechanisms in the context of autoimmunity. We are searching for a candidate to join a team exposed to cutting-edge technologies in a scientifically fertile environment that tackles outstanding scientific questions searching for innovative solutions. We are looking for someone who is passionate about cellular and molecular immunology as well as individual growth and development.

As the Senior R&D Specialist, a typical day might include the following:

- Developing and optimizing disease mouse models of autoimmune and inflammatory diseases and analyzing associated pathologies by flowcytometry (RNASeq, histology, ELISA, MSD)
- Establishing and executing cell-based assays to screen candidate antibodies for various research programs
- Performing ELISAs and/or MSDs to measure cytokine levels and determine antigen binding
- Analyzing data and interpreting novel findings and effectively communicating results during internal and external meetings
- Troubleshooting methodological and technical issues
- Collaborating proactively with team members to coordinate complex in vivo experiments, and with other departments for cross-functional efforts
- Ability to independently design, plan, execute experiments, maintain lab notebook, and communicate data in a timely manner is required
- Maintaining laboratory equipment and ordering supplies/reagents to ensure a safe, efficient work environment

This role might be for you if:

- You want to contribute to project advancement by developing and refining new methods and technologies
- You are highly organized and motivated while paying attention to detail
- You are adaptable to changing priorities and strive to implement and develop new skills
- You are a self-starter who can work independently and collaboratively in a fast-paced environment

To be considered for this opportunity you should either possess the following: MS degree within immunology, biology, biochemistry or related field combined with 6+ years of relevant lab research experience or a BS degree with 8+ years of related experience. Experience with proper handling and care of mice, general surgical techniques and collection of tissue samples and blood is required. Previous work with mouse models of autoimmune or inflammatory disease is highly desired; experience in mucosal and/or neuro-immunology is a plus. We need someone who demonstrates hand-on experience with cellular and molecular biology techniques including isolation and culture of cell lines and primary cells (immune cells of human and mouse origin). Experience with multi-cellular assays multi-color flow cytometry, ELISA (MSD etc), functional assays (e.g. proliferation, cytokine production, etc.). Experience with single cell isolation and preparation for RNASeq profiling/sequencing data is desired.
Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.