AbbVie

Senior Scientist I/II, Analytical Development

Employer
AbbVie
Location
Worcester, MA, United States
Posted
Sep 18, 2020
Ref
2004544
Required Education
Doctorate/PHD/MD
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie is searching for a highly motivated individual to fill a Senior Scientist II position in the Protein Analytics Department at AbbVie Bioresearch Center in Worcester MA. The Protein Analytics Department is responsible for qualification and execution of analytical methods and characterization studies to provide product and process understanding as well as analytical CMC management for development of AbbVie biopharmaceutical pipeline from discovery through commercial stages.

Protein Analytics is seeking a highly experienced, motivated and team-oriented individual for an important role supporting development and registration of AbbVie's biologic pipeline of preclinical, clinical and commercial products. The successful candidate will be a member of the mAb/ADC analytical development team responsible for development and execution of various separation methods (CE, LC, iCIEF, etc.) and application of robotic liquid handler platforms (Protein Maker, Hamilton Star, Tecan) to support the CMC development of AbbVie early and late phase products and processes throughout the drug development lifecycle.

Key Responsibilities:

  • Independently develop and apply capillary electrophoresis, and HPLC methods separation as well as other analytical methods to enable biological analytical development
  • Develop, qualify/validate, and transfer fit-for-purpose release and stability methods to QC.
  • Provide technical support to QC testing occurring at internal and external GMP testing laboratories.
  • Represent analytical function in the CMC program team; represent the Protein Analytical Chemistry Group as a subject matter expert on cross functional teams. Lead the development of analytical control strategy for biologic programs
  • Plan and author characterization, comparability, and quality sections of regulatory submissions (INDs/CTDs).
  • Identify and lead analytical innovations to further scientific capability of the group.


Qualifications

Qualifications:

  • PhD Degree and 0-2+ years or MS with 8+ years of experience within Biochemistry, Chemistry, Analytical Chemistry, Biophysics (or related discipline) in industry or academia.
  • Extensive hands-on experience with chromatography, electrophoresis, and other analytical techniques
  • Experience with CMC analytical development of monoclonal antibodies or related biotherapeutic proteins is a plus.
  • Must have strong written and verbal communications skills.
  • Ability to work effectively cross-functionally in anticipating and responding to overall program development needs
  • Demonstrated record of independent thought, creativity and scientific accomplishment
  • Self-motivated with the ability to act with urgency and passion
  • Ability to make thoughtful, integrated, timely and meaningful recommendations and/or decision and take corresponding actions


Key Leadership Competencies:

  • Delivers business results while also positioning AbbVie for long-term success
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality


Significant Work Activities
N/A
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.