Principal Scientist

Location
Gaithersburg, MD, US
Posted
Sep 16, 2020
Ref
675854400
Hotbed
BioCapital
Required Education
Bachelors Degree
Position Type
Full time
Those who join Emergent BioSolutions feel a sense of ownership about their future. You will excel in an environment characterized by respect, innovation and growth opportunities. Here, you will join passionate professionals who advance their scientific, technical and professional skills to develop products designed-to protect life.

The Principal Scientist position is involved in the development, optimization and technical transfer of Downstream purification processes for recombinant proteins, mAb, and virus based vaccines.

ESSENTIAL FUNCTIONS
Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions.

• Support, design, and apply manufacturing and purification processes for the production of protein candidates.
• Serve as the Technical Lead for multiple projects by developing scopes of work and technical plans.
• As the Technical Lead, oversee scientific projects executed by the Operations team.
• Develop scalable chromatographic techniques for the purification of protein candidates.
• Optimize and scale-up purification processes for transfer to a contract manufacturing organization for GMP manufacture.
• Assist in the technical transfer of purification processes to a relevant CMO.
• Invention of suitable in-process controls in order to follow the purification process.
• Generate technical documents capturing the development of purification processes.
• Technical review of draft batch manufacturing records.
• Perform intellectual property sign-off and scientific review of Emergent generated data.
• Report project progress on a regular basis, both internally and to Customers.
• Actively train other members of the Drug Substance Development team.

The above statements are intended to describe the nature of work performed by those in this job and are not an exhaustive list of all duties. Nothing in this job description restricts managements right to assign or reassign duties and responsibilities to this job at any time which reflects management's assignment of essential functions.

MINIMUM EDUCATION, EXPERIENCE, SKILLS
• PhD in Biochemistry or related field with a minimum of 8 years of experience.
• In-depth knowledge of purification and filtration techniques.
• Experience working at both lab and manufacturing scale.
• Knowledge of fermentation (eukaryotic and prokaryotic systems) and analytical techniques.
• Ability to solve complex and varied problems independently.
• Experience with statistical design of experiment and analytical data analysis.

PHYSICAL/MENTAL DEMANDS AND WORK ENVIRONMENT CHARACTERISTICS
The physical/mental demands are representative of those that must be met by an individual to successfully perform the essential functions of the job.

The work environment characteristics described here are representative of those an individual would encounter while performing the essential functions of the job.

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

There are physical/mental demands and work environment characteristics that must be met by an individual to successfully perform the essential functions of the job. This information is available upon request from the candidate.

Reasonable accommodations may be made to enable individuals with disabilities to perform all essential functions.

Emergent BioSolutions is an Equal Opportunity/Affirmative Action Employer and values the diversity of our workforce. Emergent does not discriminate on the basis of race, color, creed, religion, sex or gender (including pregnancy, childbirth, and related medical conditions), gender identity or gender expression (including transgender status), sexual orientation, age, national origin, ancestry, citizenship status, marital status, physical or mental disability, military service or veteran status, genetic information or any other characteristics protected by applicable federal, state or local law.

Information submitted will be used by Emergent BioSolutions for activities related to your prospective employment. Emergent BioSolutions respects your privacy and any use of the information submitted will be subject to the terms of our Privacy Policy .

Emergent BioSolutions does not accept non-solicited resumes or candidate submittals from search/recruiting agencies not already on Emergent BioSolutions' approved agency list. Unsolicited resumes or candidate information submitted to Emergent BioSolutions by search/recruiting agencies not already on Emergent BioSolutions' approved agency list shall become the property of Emergent BioSolutions and if the candidate is subsequently hired by Emergent BioSolutions, Emergent BioSolutions shall not owe any fee to the submitting agency.