Bristol Myers Squibb Company

Sr. Research Investigator (NMR Spectroscopy/Instrumentation Specialist)

Location
New Brunswick, NJ, United States
Posted
Sep 16, 2020
Ref
R1528647
Required Education
Doctorate/PHD/MD
Position Type
Full time
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Position Description

Our Chemical Process Development Analytical Department is looking for an NMR instrumentation specialist for the Isolation and Structure Elucidation (ISE) group, located at our New Brunswick, NJ campus. Our ISE team is responsible for the application of NMR and high-resolution MS to the characterization of chemical species in both small molecule and biologic therapeutics. The group supports all pharmaceutical development and commercial problem solving for both process and formulation development.

The successful candidate will be responsible for, but not limited to, troubleshooting hardware, software issues and maintenance for state-of-the-art, high-resolution NMRs (400-600 MHz) with conventional, and cryoprobe technology and flow probes for reaction monitoring capabilities. Operational oversight, troubleshooting and training for high-resolution open access NMRs are also in scope. In addition to instrumentation responsibilities, the candidate will be responsible for isolation of impurities and degradants, solving chemical structures with 1D and 2D multinuclear NMR techniques, evolve our biologics NMR capability, evaluate, and implement new NMR instrumentation, software and methodology.

The successful candidate will have a passion for solving challenging analytical problems with an ability to provide focused written communication and oral presentations, which highlight the impact and innovation of the work. Influence scientists and initiatives that improve efficiency, productivity and evolution of our structure elucidation capabilities. Routinely engaged in active discussions within team meetings, define and agree to action items, and delivers high quality data within timelines. Collaborate with other subject matter experts to continually develop project knowledge, meet project goals and enable capability amongst our department's organic chemists and chemical engineers.

Qualifications
  • Ph.D. in chemistry or a related discipline with at least three years of post-Ph.D. industrial or academic experience
  • Experience with troubleshooting NMR hardware and software (Bruker preferred) including magnets, consoles, conventional and cryo probes, autosamplers and workstations (Windows and Linux)
  • Solid understanding and application of NMR theory to solve chemical structures and interactions of small molecules and/or biologics
  • Proficient in the interpretation of multinuclear 1D and 2D NMR data preferred.
  • Excellent oral and written communication skills, problem solving ability and leadership skills
  • Familiarity with LC-HRMS, MS/MS and other spectroscopic and chromatographic methods are desirable


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.