Research Associate, IOCT Gene Engineering and Delivery

Location
Seattle, WA, United States
Posted
Sep 16, 2020
Ref
R1529850
Required Education
Bachelors Degree
Position Type
Full time
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Job Description

Bristol Myers Squibb is looking for a highly motivated and dynamic individual to join the Immuno-Oncology & Cellular Therapy Gene Engineering and Delivery team in Seattle. The primary focus of the Research Associate role will be to design, clone, characterize and produce viral vector constructs that will be the gene delivery tools for developing cancer immunotherapies.

The key deliverables for this role are: 1) execute on generating a variety of viral vector constructs 2) show competency in cell culture, transfection, and transduction of mammalian cell lines and primary T-cells 3) generate viral vector to support research programs 4) analyze and communicate data to key stakeholders.

Primary responsibilities:
  • Design and clone viral vector constructs
  • DNA/RNA extraction and purification
  • Culture mammalian cell lines to be used for the production and assessment of vector
  • Set up and run molecular biology and cellular assays to evaluate viral vector
  • Work to develop and improve viral vector production and characterization protocols
  • Work with other team members to develop and evaluate technical feasibility of novel gene delivery methods
  • Process and analyze data, review, and report results
  • Maintain accurate and detailed electronic laboratory notebook and documentation
  • Summarize and present data in group meetings and in written form
  • Work independently as well as with other team members and cross-functional teams to perform and troubleshoot experiments or assay performance


Required Qualifications:
  • B.S./B.A. degree in a scientific discipline and 2+ years of hands on experience in relevant field of research
  • Strong molecular biology skills; cloning, PCR, RT-PCR, mRNA and DNA prep.
  • Experience with tissue culture techniques including but not limited to transfection of mammalian cell lines and transduction of T-cells
  • Strong organization, time management and problem-solving skills with attention to detail
  • Ability to independently design and troubleshoot experiments
  • Ability to strive in a fast-paced, creative and goal-oriented environment and drive tasks and projects to completion under timelines
  • Outstanding written, visual, and oral communication skills.

Preferred Qualifications:
  • Experience producing and working with viral vector.
  • Flow cytometry


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.