Head of Portfolio and Program Management

Location
Louisville, KY, United States
Posted
Sep 15, 2020
Ref
1191684256
Hotbed
NextGen Bio
Required Education
Bachelors Degree
Position Type
Full time

Talaris Therapeutics, Inc.("Talaris") is developing a breakthrough, one-time cell therapy to enable patients who receive a living donor kidney transplant to no longer require lifelong immunosuppression, without rejecting their donated organ. Achieving durable, drug-free immune tolerance to a donated organ has been referred to as a "Holy Grail" of organ transplant. In a ground-breaking, phase 2 study conducted between 2008 - 2016, our lead therapy, FCR001, enabled 70% of patients to be weaned off all immunosuppression within 12 months of their kidney transplant. No tolerized patient has had to resume immunosuppression. We have followed these patients for an average of almost five years since their transplant, and the longest for over ten years. Our single-dose cell therapy has also shown the potential to induce durable remission of certain types of severe auto-immune diseases, and to benefit other solid organ transplant patients. Talaris has announced a $100M private financing from leading life sciences investors and has initiated a Phase 3 pivotal trial of our therapy in living donor kidney transplant patients. We also expect to initiate two Phase 2 trials of our therapy in additional indications in 2021. Our cell processing facility and most of our operations are based in Louisville, KY, and we also have a corporate office in Boston, MA.

Position Summary

Talaris is seeking a Head of Portfolio and Program Management to develop and lead the program management function. This newly created position will play a key role in establishing program management processes and tools, identifying risks and developing mitigation plans, and coordinating cross-functional plans and timelines across all programs. This role will initially focus on hands-on Program Management for Talaris' existing programs, ensuring that Clinical Development, Regulatory, CMC and Research strategies and plans are integrated and aligned to deliver on company and product goals. This role will also be responsible for building out an appropriate program management function for Talaris, including identifying roles required, participating in hiring and onboarding, delegating responsibilities, and supervising team members within this function. Additionally, this role will serve as an intermediary between the functions and the Leadership Team, working through issues and ensuring that cross-functional plans are harmonized, key decisions are made in a timeline manner, and communications flow smoothly across functions.

Primary Responsibilities

  • Build, lead, manage, and maintain the Program Management function, partnering with functional leads to ensure team effectiveness and operational excellence
  • Coordinate effective execution of Integrated Development Plan (IDP) across functions; develop and manage detailed project plans to support achievement of objectives outlined in the IDP
  • Communicate a shared and bold vision for the program across all levels of the organization, including Board of Directors
  • Develop team charters and communication pathways to streamline meeting management
  • Drive agenda items for discussion and alignment, and partner with Leadership Team, Portfolio Steering Committee, and Program Team to address key topics within the appropriate governance forums
  • Coordinate and communicate responsibilities and requirements for organizing team meetings, distribution of meeting summaries, communication of decisions and action items
  • Collaborate with the Program Team to develop Key Performance Indicators (KPIs); implement process to track progress against short-term and long-term goals
  • Architect scenarios to inform decision making and program planning; ensure that the right skills and capabilities exist on the team to effectively execute on the program plan
  • Inspire team members to achieve ambitious goals, providing feedback and mentorship to drive high performance; build trust and respect across the team and its members; model behaviors and support team members
  • Collaborate closely with Finance and functional leads to provide strategic oversight for program budgets and resourcing, including long-range financial planning across programs


Qualifications:

 

  • Bachelor's degree required, with a concentration in a scientific discipline strongly preferred
  • Advanced scientific degree (e.g., MS, PharmD, Ph.D.) or a combination of equivalent experience and training preferred
  • Project Management certification / training (PMP) and / or coursework & training in Project Management preferred
  • 10+ years of program management experience, including relevant drug development experience with strong track record of success in cross-functional team leadership
  • Strong holistic perspective of drug development process across different functional streams; experience through the entire drug development lifecycle is a plus
  • Experience in the use and understanding of the value of technology in managing milestones, resource planning and integrating interdependencies and cross functional teams
  • Demonstrated ability to develop deep understanding of therapeutic areas and optimal development and overall business strategies; experience in cell or gene therapy preferred
  • Demonstrated success in building a program management function in a rapidly growing company, including implementation of program management process and tools
  • Team leadership, project management and organizational skills, along with problem solving, negotiation skills, conflict resolution, and team building skills
  • Demonstrated ability to communicate effectively to a broad array of internal and external stakeholders
  • Willingness to "roll up sleeves" and contribute where needed to achieve the team's objectives; ability to wear multiple hats and fill in when needed


Apply: Please submit resume or CV and cover letter to hiring@Talaristx.com

Talaris is fully committed to equality of opportunity in all aspects of employment. It is the policy of Talaris to provide equal employment opportunity to all employees and applicants without regard to race, color, religion, national or ethnic origin, military status, veteran status, age, gender, gender identity or expression, sexual orientation, genetic information, physical or mental disability or any other protected status.