AbbVie

Scientist I, Pharmaceutics - Drug Product Development

Employer
AbbVie
Location
Worcester, MA, United States
Posted
Sep 15, 2020
Ref
2003540
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 25,000 people worldwide and markets medicines in more than 170 countries.

Drug Product Development is responsible for designing and developing formulations that enable delivery of AbbVie's candidate molecules in a dosage form suitable for preclinical or clinical studies. AbbVie is seeking a highly motivated, collaborative scientist with a proven track record in physicochemical characterization of small molecule candidates and application of drug delivery approaches in preclinical development.

Key Responsibilities include:

  • Execution of studies to characterize the physicochemical properties of candidate molecules in preclinical development
  • Design and preparation of formulations, including solutions/suspensions/emulsions, to enable preclinical acute and chronic in vivo studies
  • Interpret and communicate results from characterization and formulation studies to advise the selection of molecules with properties suitable for development


Qualifications

Qualifications:

  • BS (5+ yrs. experience) or MS (2+ yrs. experience) in Pharmaceutics, Pharmaceutical Sciences, or Chemistry.

Preferred:

  • Familiarity with the role that physicochemical properties play in drug delivery and formulation design.
  • Working knowledge of physiological barriers to drug absorption, including various potential transport mechanisms.
  • Working knowledge of typical formulation approaches and routes of administration (i.e. IV, SC, IP, PO) across multiple species.
  • Experience with analytical approaches toward physicochemical characterization of pharmaceutical dosage forms (i.e. HPLC, UPLC, MS, DSC, TGA, PXRD, dissolution)
  • Experience with various milling techniques and particle size analysis
  • Understanding crystalline and amorphous materials and their impact on drug development
  • Excellent oral and written communication skills.
  • Demonstrated ability to work collaboratively in a cross functional team setting.

Key AbbVie Competencies:

  • Builds strong relationships with peers to facilitate communication and enable higher performance.
  • Learns fast, grasps the "essence" and can change the course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others and nurtures innovation

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
IC
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.