Scientist/Sr. Scientist, Protein Therapeutics
- Employer
- Nektar Therapeutics
- Location
- San Francisco, CA, United States
- Start date
- Sep 12, 2020
View more
- Discipline
- Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
Nektar has an exciting opportunity for a Scientist/Sr. Scientist, Protein Therapeutics to join their team.
Nektar is seeking a Scientist/Sr. Scientist, Protein Therapeutics with expertise in proteins and protein characterization to join our protein analytics team to characterize proprietary polymer-protein or polymer-peptide conjugates. To succeed, you will need to apply knowledge of protein chemistry, characterization, and protein-protein interaction techniques to design and develop appropriate data sets that support company initiatives. You will contribute to the planning and execution of scientific experimentation to support the protein therapeutic pipeline for the company. You will develop characterization methods for Research and support tech transfer for manufacturing. You will manage workflow among a complex set of projects, collaborators and sites. This is a hands-on bench position that contributes to and supports the company's research and development efforts to create high value therapeutics to address unmet medical needs.
Responsibilities:
- Independently develops analytical methods for characterization, lot release and technology transfer for candidate protein molecules. Will be responsible for performing technology transfer to clients or internal Process Development/Manufacturing.
- Works on multiple projects simultaneously, where coordination of efforts among various sites and attention to critical timelines is essential to success.
- Works on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors.
- Exercises judgment within broadly defined practices and policies in selecting methods, techniques and evaluation criteria for obtaining results.
- May determine methods and procedures on new assignments. Serves as an in-house consultant.
- Synthesizes multiple data sources and draws general, non-obvious conclusions. Defines complex problems, develops approaches and develops experiments with sound judgment.
- Interfaces with various departments, customers and partners. Puts work practices in context with larger team and participates in the implementation of change when required. Plans and coordinates activities with other team members.
- Critically analyzes complex data and interprets experimental results. Interfaces, works with and supports various departments at multiple locations.
- Plans and coordinates activities with other scientists and team members.
- Writes complex reports and protocols. Ensures thorough documentation of laboratory activities; technical reports detailing development efforts, analytical development reports, batch records, or technology transfer reports. Contribute to patent applications and IND filings as needed.
- May be expected to mentor and train individuals. Oral presentations will be periodically required. Travels to client site or other company functions as needed.
- A PhD in Biochemistry, Chemical Engineering, Chemistry or related field required. A minimum of 2-5 years of protein characterization experience in a research and/or development environment is required. Post-doctoral work may serve as experience. Exceptional non-PhDs with demonstrated capabilities or relevant industrial/biotechnology experience may be considered. Title is commensurate with experience.
- Demonstrated knowledge of protein characterization
- Prior experiences in with immunology or immune-oncology targets is desired
- Must have hands-on experience in protein chemistry and protein-protein interaction analysis and be thoroughly familiar with basic protein chemistry tools such as SDS-PAGE, IEF and western blotting. Experience in polymer chemistry or small molecule chemistry is a plus.
- Experience with affinity chromatography, IEX, RP, SEC, or other methods, both for purification and for analytical development is expected.
- Experience with tissue culture and associated molecular biological techniques is desired
- Experience with ELISA and flow cytometry is a plus
- Familiarization with structural biology and molecular modeling a plus.
- Must be able to clearly communicate scientific information. Must have good interpersonal skills and be willing to work as part of a team. Must have the ability to effectively work with all levels of scientists and management, including foreign collaborators. Excellent scientific writing, communication, presentation, documentation, and computer skills required. Ability to work internationally and across multiple corporate sites.
- Must be a team player and mentor and work closely with both research efforts and process development. Must be able to exert influence effectively. Must be able to demonstrate sound judgment and problem-solving capabilities.
- Strong organizational skills are required.
- Must be able to demonstrate broad success in technical proficiency, scientific creativity, collaboration with others and independent thought. Must represent the leading edge in field, while able to demonstrate expert knowledge in scientific principles and concepts both internally and externally with sustained performance and significant accomplishment on at least one area.
- Performance of tasks essential to the job function may require the employee to work directly with, handle, or otherwise come into contact with chemicals or pharmaceutical agents. Employees may be required to enroll in a medical surveillance program based on the potential exposure to certain health hazards encountered as a result of their job function. Must be able to lift small pieces of laboratory equipment and carry 4L solvent bottles when needed. Occasional work in a cold room (refrigerator temperature) may be required.
- Must be comfortable and independent spending a majority of time doing bench-top science.
- Ability to multi-task in an extremely dynamic environment while providing high-quality analytical support in a professional, pleasant, and tactful manner is a necessity.
Company
Nektar Therapeutics is a research-based development stage biopharmaceutical company that discovers and develops innovative medicines in areas of high unmet medical need. Our R&D pipeline of new investigational drugs includes treatments for cancer and auto-immune disease. We leverage Nektar's proprietary and proven chemistry platform in the discovery and design of our new drug candidates. Our success is rooted in four key elements: our track record reflected by a portfolio of successful approved medicines which emanated from our chemistry platform and are made available globally by our pharmaceutical partners, our unique research and development pipeline of new investigational medicines in cancer and immunology, our proprietary and proven science and technology approach that fuels our discovery efforts and our team of dedicated scientists, clinicians and employees focused on bringing new medicines to patients with debilitating diseases.
Stock Symbol: NKTR
Stock Exchange: NASDAQ
- Website
- http://www.nektar.com/
- Phone
- 415-482-5300
- Location
-
455 Mission Bay Blvd South
San Francisco
California
94158
United States
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