Biomarker Research Scientist
BioSpace is partnering with an early-stage biopharmaceutical company whose focus is on the discovery and development of novel immunomedicines for the treatment of cancer and other immune-related diseases. We are seeking a highly motivated Scientist to support translational science and biomarker discovery efforts for an Immuno-oncology pipeline. As part of the biomarker group within the translational research department, you will develop, integrate, and implement innovative biomarker strategies for Oncology clinical development programs, including validation and integration of biomarker assays into clinical trials.
Substantial expertise in oncology, biomarker discovery, companion diagnostics, and translational research is highly desirable. The individual will serve as a study biomarker leader and will be responsible for designing and implementing biomarker strategy for studies within the company's immunotherapy portfolio. In addition, the incumbent will ensure successful execution of diagnostic strategies with collaborators and service providers. The ideal candidate will be familiar with cutting edge biomarker discovery techniques, including NGS, Nanostring and multi-plex IHC technologies, assess and implement novel biomarker-driven surrogate endpoints, and present biomarker focused clinical data, and to promote collaborative efforts to forward the biomarker sciences field in general.
- The role will include overseeing and validating accurate data acquired on-site by flow cytometry and Nanostring nCounter and Digital Spatial Profiler (DSP)
- Ensure optimal usage of samples from clinical trial used by biomarker group, including storage and distribution within the group, to service providers and to collaborators.
- Identify novel technologies to be evaluated and implemented by the biomarker group.
- Work both independently and collaboratively with a multidisciplinary team of Scientists and Project leader to design, execute and interpret biomarker studies for multiple projects.
Required Education, Experience, & Qualifications
- PhD, MD or PhD/MD degree in a relevant scientific field (e.g. cancer biology, immunology).
- Experience in Biomarker Development and Translational Medicine as part of clinical drug development for cancer.
- Hands-on knowledge in biostatistics.
- Hands-on experience with Nanostring’s GeoMx Digital Spatial Profiler (DSP) and flow cytometry.
- Minimum of 3-5 years postdoctoral basic or translational research experience in either academic and/or in an industry setting.
- Outstanding organizational skills and experience with distribution and precious biological samples.
- Presentation and communication skills
- Successful demonstration of initiative, teamwork, collaboration and technical expertise as an independent and creative scientist