Senior Scientist I/II, Molecular and Cellular Biology

Worcester, MA, United States
Sep 06, 2020
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company that combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world's most complex and serious diseases.

AbbVie Immunology, located in Worcester, MA offers a unique working environment for drug discovery. Our mission is to identify break-through therapies for inflammatory and auto-immune diseases that will have a remarkable impact on patients' lives.

We are seeking a Senior Scientist responsible for the validation of drug targets and the characterization of lead molecules by employing mechanistic and disease-relevant in vitro model systems. The successful candidate will be responsible for conducting in vitro assay development and execution using high-throughput screening technology, and they will be engaged in target validation studies. Additionally, the incumbent will make strategic contributions to projects and may supervise one or more research associates.


Required Skills:

  • Development and execution of robust biochemical and cellular assays to support drug discovery programs
  • Characterization of drug candidate mechanism of action with in vitro systems
  • Contribution to discovery project science and strategy
  • Generation, analysis, interpretation, and quality control of quantitative data
  • Effectively organize and communicate research progress and activities through oral and written presentations
  • Maintenance of accurate and current records of research

Preferred Skills:

  • Experience with cellular immunology, including isolating and measuring functional responses of primary immune cells and phenotyping by flow cytometry
  • Experience with molecular biology techniques such as cloning, cell line generation, transcript analysis, and CRISPR
  • Experience with assays for measuring enzyme activity, ligand-binding, phospho-proteins, calcium mobilization, gene expression, and protein expression
  • Experience in the development, automation, and execution of biochemical and cellular assays to characterize drug candidate properties

Basic Qualifications:

Position will be hired based on level of experience

  • BS, MS, or PhD in Biochemistry, Molecular Biology, Cell Biology, Immunology or related discipline with typically 10-12 (BS), 8-10 (MS), or 0-4 (PhD) years of relevant post-degree experience
  • Candidate must be highly collaborative and thrive in a dynamic, multi-disciplinary environment
  • Strong familiarity with spreadsheets, databases, and curve-fitting programs
  • Strong organizational, communication, and inter-personal skills

Significant Work Activities
Yes, 5 % of the Time
Job Type
Job Level Code
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.