Research Associate II, Molecular and Precision Medicine Microscopy
- Employer
- Frederick National Laboratory for Cancer Research
- Location
- Frederick, MD, USA
- Start date
- Sep 5, 2020
View more
- Discipline
- Clinical, Science/R&D, Research
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- BioCapital
Job Details
The Clinical Pharmacodynamics Biomarkers Program is responsible for identification of biomarkers of response to new targeted agents entering clinical trials in the Developmental Therapeutics Program of the National Cancer Institute. The scope of work includes assay design, development, validation, fitness for purpose testing, transfer of assays to clinical laboratories, and clinical specimen analysis when required. PADIS facilitates mechanistic and performance analysis of putative anti-cancer agents, diagnostic tests, and therapeutic interventions to clinical applications, including distinct molecular signatures for cancer, refined molecular assays, and state-of-the-art imaging techniques that are too high-risk for industry or academia to pursue.
KEY ROLES/RESPONSIBILITIES
- Learn and become proficient with multiplex biomarker assays using immunofluorescence microscopy
- Operate confocal microscope and state-of-the-art imaging equipment
- Learn and become proficient on imaging fixed xenograft tissue sections and clinical specimen biopsies by following detailed technical SOPs
- Learn and become proficient on state-of-the-art image analysis software to report quantitative biomarker measurements
- Perform data analysis on multiple types of image files using advanced quantitative image analysis software following detailed technical SOPs for image analysis
- Handle large data sets
- Report quantitative clinical data precisely, accurately and completely
- Assist in the transfer of validated assays and SOPs to operators in external labs through detailed training of others
BASIC QUALIFICATIONS
- Possession of a Bachelor's degree from an accredited college/university in a field related to biomedical research or four (4) years equivalent experience in the appropriate field in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency
- In addition to educational requirements, a minimum of five (5) years related biomedical or clinical experience
- Experience following SOPs and maintaining precise records
- Experience preforming high complexity testing
- Experience reporting data accurately and reliably
- Ability to master novel technologies and instrumentation
- Ability to communicate with project team in a demanding scientific environment
- Ability to be flexible to meet changing needs
- Proficiency with Microsoft Office (Outlook, Excel, Word and PowerPoint)
- Must be able to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
- Experience with imaging instrumentation and technologies (Nikon, Zeiss, Leica)
- Experience with confocal microscopy
- Experience with image analysis software
- Experience with GraphPad software
- Experience performing microscope-based assays
JOB HAZARDS
- This position is subject to working with or have potential for exposure to animal(s) and/or animal material(s).
- This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations.
- This position is subject to working in or have the potential to exposure to high noise levels for extended periods of time requiring medical clearance.
- This position is subject to the environmental conditions such as working outdoors, high humidity areas indoors, dampness and chilling, dry atmospheric conditions, etc. as part of the job.
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
#readytowork
Company
A rewarding career with global impact
Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.
Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.
We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.
Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.
Discover why joining the Frederick National Laboratory team could be the most important career step you take
- Website
- https://frederick.cancer.gov/
- Phone
- 301-846-1000
- Location
-
8560 Progress Drive
Frederick
MD
21701
US
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert