Bristol Myers Squibb Company

Director MM Disease

Jersey City, NJ, United States
Sep 04, 2020
Science/R&D, Pathology
Required Education
Position Type
Full time
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

About Bristol-Myers Squibb

Bristol Myers Squibb is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of novel therapies for the treatment of cancer, cardiovascular and inflammatory diseases through gene and protein regulation.

BMS R&D is at a critical and exciting phase of development. As it expands and integrates its portfolio, there is an opportunity for a dynamic and resourceful individual to lead our efforts in Translational Development at our site in San Francisco.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Translational Medicine at BMS

Translational Medicine is part of the Global Research and Early Development organization in BMS and leads early stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. The Heme Translational Development Disease Team (TDDT) is a late translational group that supports multiple disease areas of interest including Myeloma, Lymphoma, CLL and other hematological malignancies. This group integrates scientific and business insights of multiple functions and lead the development of translational strategies at the franchise level and implement them in project teams to maximize the potential of Celgene drugs.


Reporting to the VP, Translational Medicine, the incumbent will be part of the translational group based in Summit NJ and will help develop translational disease and asset strategies in Multiple Myeloma for approval or life-cycle management of our pipeline. Key responsibilities of this role are to act as key Myeloma disease scientist to assist in developing translational strategy working with translational scientists and cross-functional disease team and thematic centers of excellence, build and manage a laboratory group working in translational OMICs platforms, manage strategic disease collaborations and projects.

Technical Skills:
  • In-depth understanding of multiple myeloma, clinical landscape, evolving therapy, competitive scenario
  • Strong understanding of clinical, translational and mechanistic data with IMiDs in NDMM and RRMM setting
  • Strong background in strategy development preferably in Multiple Myeloma
  • Understanding of late-stage drug and translational development process
  • Proven ability to work with global disease teams to develop strategies to support life cycle management efforts tailored to regional markets (i.e, US, EU, CAN)
  • Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses
  • Proven scientific/project leadership expertise (working in teams, managing people/projects)
  • Ability to synthesize complex scientific and business problems into strategy and tactics
  • Basic understanding of IP, contracting terms and provisions

  • Leads the development of disease specific translational annual goals and objectives for the late group (for internal /external, translational collaboration, compound specific plans etc), ORQs, and is accountable for their progress monitoring in association with TD scientists
  • Assists in developing and maintaining group budget and workforce plan
  • Represents Translational Development in cross-functional strategy teams
  • Interfaces with commercial including early commercialization group and Medical Affairs to provide scientific support for cross-functional TD goals
  • Assists in managing key strategic and/or collaborative projects along with TD scientists
  • Supports regulatory submissions, regulatory interactions, writes translational sections for regulatory response and answers to regulatory queries for the TD group
  • Communicates regularly and prepares and makes presentations within the department and externally as required
  • Participates in translational research in the Summit lab of Celgene


The candidate will be at the interface with asset, disease and lab teams, with the aim of providing the successful implementation of translational strategies in BMS pipeline development

Technical Skills:
  • Scientific and technical expertise
  • Proven track record of success in drug discovery and development.

  • Genomics analysis from human clinical samples, cell screen samples and clinical trial support (defined clinical experiments from the development teams). This includes development of a high dimensional bioinformatics.
  • Clinical PD or Biomarker assays, translated from discovery (if applicable or appropriate) or developed specifically for early clinical use, assessing feasibility and applicability for companion diagnostics
  • Application of model systems (in collaboration with the disease biology and in vivo pharmacology groups) beyond those routinely employed by discovery teams that aid in patient stratification/response and compound use, either in-house or as a collaboration
  • Translational Development representation to the Development Project teams
  • Participate in formulating disease area strategy for target selection and validation
  • Evaluating, in conjunction with BD and the established teams, the potential in-licensing opportunities that may include potential therapeutics, emerging technologies, processes or capabilities that will enhance our Drug Discovery and Early Development efforts.
  • Being part of the team responsible for establishing key alliances with academic centers, co-operative groups and government agencies for cost effective implementation of BMS early and late development strategy

  • Track record in large and small companies, leading innovative efforts to deploy technologies and assays for enhanced translational capabilities
  • Excellent communication, managerial and scientific qualities are expected
  • Ability to interact effectively across boundaries using influencing and relationship building skills.
  • Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.

Other Attributes:
  • A problem solver who creatively and knowledgably transcends departmental function to act as a resource to entire research effort and senior managers in development.
  • Identifies issues early and proposes innovative solutions.
  • Communicates within the larger organization and external community.
  • Provides expert guidance to multi-disciplinary teams and senior management.
  • A leader whose scope of influence stretches across Celgene.
  • A leader who influences external scientific community.

Requirements & Education:
  • PhD
  • 10-12 years industry experience

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.