Bristol Myers Squibb Company

Associate Scientist, Preclinical Biology - Late Stage In vitro

Location
Seattle, WA, United States
Posted
Aug 31, 2020
Ref
R1526069
Required Education
Bachelors Degree
Position Type
Full time
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The CAR T and TCR Biology team in the Immuno-Oncology Cell Therapy Thematic Research Center has an opening for a highly motivated and creative Associate Scientist with a dedication to discovery and development of novel engineered CAR T and eTCR T cell therapeutics for the treatment of cancer. The successful candidate will have experience setting up in vitro functional assays to measure T cell function: including proliferation, cytokine production, phenotypic analysis and cytotoxic activity. Flow cytometry experience is essential. In addition, this position will work with senior researchers to execute studies, analyze data and communicate results. This position is ideal for the innovative scientist who is driven and passionate about cell therapy in a fast-paced, collaborative environment.

Responsibilities include but are not limited to:
  • CAR T cell and eTCR T cell generation, expansion, characterization and cryopreservation
  • CAR T cell and eTCR T cell phenotypic analysis using flow cytometry. In vitro functional evaluation using T cell/Tumor co-culture assays
  • Cytotoxic activity using IncuCyte
  • Collaborating with scientists and other researchers to design, perform and optimize in vitro experiments
  • Maintaining notebooks with detailed documentation of protocols, study designs and results
  • Perform data analysis and interpretation
  • Organize findings for effective communication to supervisor and colleagues

Qualifications:
  • B.S. in biological science, immunology or related discipline with at least 6 years of relevant work experience or M.S. with minimum of 2 years of relevant work experience in T cell biology
  • Experience with in vitro technologies typically employed to assess T cell functionality including but not limited to MSD, IncuCyte-based assays, multi-parameter flow cytometry for phenotypic characterization of T cells, T cell activation assays, T cell proliferation analysis. Experience with imaging technologies desired but not required
  • Able to recognize potential problems and recommend/develop appropriate solutions
  • Ability to work productively as both team member and as individual contributor
  • Strong communication skills for working with cross-functional teams as well or cross-departmental colleagues
  • Requires strong organizational skills to ensure thorough and timely documentation of experiments,


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.