AbbVie

Senior Scientist I/II, NMR Spectroscopy - ARD

Employer
AbbVie
Location
Lake County, IL, United States
Posted
Aug 29, 2020
Ref
2006378
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative small molecule and therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines. Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

AbbVie is seeking a qualified NMR spectroscopist at our facility located in North Chicago IL. The North Chicago NMR laboratory is a core facility that provides key support for groups across AbbVie. These include the Process Chemistry, Pharmaceutical Operations and Analytical R&D. The selected candidate will be responsible for interacting closely with these groups to identify areas where NMR can provide essential information and will prioritize projects and generate/analyze data that support synthetic method development and process optimization for late stage compounds. Key contributions include structural determination of process, manufacturing and degradation impurities, quantitation of mutagenic impurities, quality control testing of incoming materials, adulteration testing, characterization of samples entering clinical studies, and investigation of on-market product issues.

On a day to day basis this individual will be responsible for the operation, maintenance, and optimization of NMR instrumentation, robotic systems, and processes for archiving and retrieving data. The lab currently has a Bruker NEO 700 MHz w/ cryoprobe, Bruker Avance III 600 MHz w/ solid state capability, Bruker Nanobay 400 MHz and a Varian MR 400 MHz system.

Qualifications
  • Bachelor's Degree or equivalent education and typically 10-12 years of experience, Master's Degree or equivalent education and typically 8-10 years of experience, PhD and typically 0-4 years of experience in the physical sciences and experience with modern NMR techniques and instrumentation for structural identification
  • Previous work experience in a cGMP (i.e. QC or equivalent) pharmaceutical laboratory setting preferred.
  • Experienced in laboratory systems (LIMS, CDS, ELN) preferred.
  • Effective writer and communicator of research or other regulatory materials.
  • Proven effective written and verbal communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
  • High attention to detail, creativity in problem solving, strong interpersonal skills and proven ability to successfully work independently and as part of teams.
  • Ability to work on multiple and simultaneous projects as part of a team in a global, fast-paced, setting where priorities may change quickly
  • Maintaining currency with regulations, for ensuring that the laboratory remains in compliance with these regulations, and for interacting with AbbVie compliance staff and FDA personnel.


Key AbbVie Competencies:
  • Builds strong relationships with peers and cross functionally with partners outside of teams to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
Yes, 5 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.