Research Scientist, Analytical Development

Employer
Kite Pharma
Location
Santa Monica, CA, United States
Posted
Aug 28, 2020
Ref
R0015045
Required Education
Bachelors Degree
Position Type
Full time
Kite is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job

Job Description

Kite is seeking a highly motivated individual with analytical development and support experience to work on innovative T cell therapy for cancer treatment. The Research Scientist of Analytical Development (AD) will be mainly responsible for deep analytical characterization of cell therapy products at different developmental stages. You will also be assisting in planning and executing laboratory studies, analyze/review experimental data and carefully document resultant information. This position reports to a Director.

Responsibilities (include but are not limited to):
  • Execute flow cytometric testing on a regular basis or as needed, in support of process development and product characterization
  • Perform data analysis, data reporting, and further statistical analysis with advanced analysis software
  • Assist in data verification to ensure data integrity
  • Maintain, calibrate and operate flow cytometry analytical equipment and BD cell sorter
  • Implement reagent titration, lot-checking, and maintain proficiency testing database
  • Transfer flow cytometry assays from the method development group to analytical testing group
  • Develop templates for standard operating procedures and analytical test methods
  • Write, review and edit accurate technical documents
  • Assist in developing, qualifying, executing and documenting ≥10 color flow cytometry methods to study and characterize processes for production of T cell therapies
  • Provide user training on instruments, sample analysis, and cross-train analysts on analytical methods
  • Coordinates activities for members of project teams in the initiation and execution of laboratory experimentation
  • Participate in sampling and study plan meetings to support different functional areas within Process Development
  • Additional responsibilities may be assigned to reflect changes in business processes.


Qualifications
  • BSc with 8+ years, or MSc with 6+ years, or PhD with no industry experience in cell therapy areas.
  • Demonstrated strong knowledge of developing flow cytometry methods, and technical knowledge of instrument, method controls
  • Proficient in operating CytoFLEX S/LX, BD FACSAria II and CliniMACS
  • Understand deep characterization knowledge in patient materials, product knowledge, and process characterization
  • Demonstrates emerging ability in developing methods, techniques and evaluation criteria for obtaining results and interpreting experimental outcomes
  • Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench
  • Ability to think critically, demonstrate troubleshooting and problem solving skills
  • Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment
  • Previous experience with other technologies is a plus
  • Excellent skill in Microsoft word, Excel, MS Teams, Prism, Diva, CytEXPERT, and FlowJo data analysis software
  • Highly collaborative with excellent interpersonal, verbal and written communication skills
  • Ability to think critically with demonstrated problem-solving and troubleshooting skills
  • Comfortable working in a fast-paced company environment with minimal direction and able to adjust workload/assignments based upon changing priorities
  • Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description


Do you want to make a real difference in the world? Come help us in our quest to cure cancer! Everyone at Kite is grounded by this common goal. Every single day, we seek to establish a direct line between that purpose and our day-to-day work. Join us in our mission!

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.