Bristol Myers Squibb Company

Research Investigator, Protein Analytics and Characterization

Location
New Brunswick, NJ, United States
Posted
Aug 28, 2020
Ref
R1527138
Required Education
Doctorate/PHD/MD
Position Type
Full time
At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The division of Global Product Supply at Bristol-Myers Squibb is seeking a highly motivated scientist to join our Sterile Products Development group. The successful applicant will be primarily responsible for the technical and strategic advancement of biologic drug candidates in support of formulation and process optimization throughout all stages of clinical and commercial drug product development.

This individual should have demonstrated detailed fundamental knowledge of protein structure and degradation mechanisms including chemical stability, physical stability and interactions with common excipients and surfaces. Hands-on experience with analytical and biophysical characterization techniques for monitoring and investigating protein dynamics, stability and higher order structure under physiologically or pharmaceutically relevant conditions is also required. Additional knowledge of chemical biology concepts, multi-domain structures and complexes, protein-conjugates and protein behavior in solid forms is also highly desirable.

The successful candidate must have a passion for problem solving and a keen sense of innovation, along with excellent interpersonal communication skills and enthusiasm for working with multidisciplinary teams for developing and advancing biologic drug products. This requires rigorous design and execution of experiments, promoting novel applications and advancements of technologies, in addition to high standards of laboratory safety, documentation, and interpretation and presentation of scientific results, both independently and collaboratively.

Qualifications:

The successful candidate must have an advanced degree in chemistry, biochemistry, engineering or related field, with 0-3 years of relevant industrial or postdoctoral experience required with a PhD degree, or a minimum of 5 years of experience with a M.S. degree.

The successful candidate must have demonstrated knowledge and hands-on experience using protein mass spectrometry (from intact to peptide levels) as well as various protein separation (chromatographic and electrophoretic) techniques. Experience or working knowledge of spectroscopic techniques (e.g. light scattering, Raman), biophysical techniques and coding/scripting for automated data analysis and molecular dynamics simulation is a plus.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.