Proteomics Bioinformatician

 

Tegmine is an early-stage, well-funded, startup that’s going to restore futures lost too soon.  We believe that the high cost of healthcare can be addressed by mixing biology, technology, and machine learning.

We’re seeking a bioinformaticion with a passion for solving complex, open-ended problems.  The scientist will  mine proteomics data to identify disease-specific protein states that will serve as drug targets.

Responsibilities

  • The primary responsibility is to work with our Proteomics Scientists to organize and analyze our mass spectrometry proteomics data sets.
  • Additional responsibilities include: employing machine learning techniques to prioritize therapeutic targets for drug development, assisting laboratory scientists with data analysis, and participating in the development of a deep-learning approach to improve mass spectrometry spectrum annotation. 

Requirements

  • Experience with processing raw proteomic data from modern mass spectrometers.
  • Experience using shotgun proteomics search engines to identify post-translationally modified proteins.
  • Experience analyzing peptide fragmentation patterns.
  • Familiarity with biological annotation and ontology resources, such as Ensembl, GO, and UniProt.
  • Ability to clearly  communicate complex ideas with co-workers. 
  • B.S. with 2 years of industrial, or academic, experience and familiarity with basic biological and statistical concepts.
  • M.S., or Ph.D., with experience in bioinformatics, machine learning, or deep learning. 

Preferences

  • Experience using Java, JavaScript, Python, R, Scala, or SQL to organize and analyze complex data sets.
  • Workflow management and execution in an GNU/Linux, or MacOS, environment using shell scripts and Docker containers.  Familiarity with Google Compute Engine is a plus.
  • Experience with deep learning frameworks, such as Keras or PyTorch.

We offer a comprehensive compensation package, including equity, paid time off, health coverage, and opportunities for professional growth & development.  We promote personal growth and team-building by sponsoring access to the wide variety of artistic & cultural events available in the San Francisco Bay Area.

We love diverse and interesting people.  We’re an equal opportunity employer and our employment decisions are made without regard to age, disability, gender, genetic background, hair, or national origin.   If you're good at what you do and are respectful of your co-workers, please inquire with the "Apply" button.