Research Associate I II/Senior Research Associate, In Vivo Pharmacology

Location
South San Francisco
Salary
Exact title commensurate with experience. Atreca is an equal opportunity employer.
Posted
Aug 26, 2020
Ref
221
Required Education
Bachelors Degree
Position Type
Full time

Who we are

Atreca is an integrated biotechnology company located in South San Francisco, California. We apply our proprietary drug discovery platform to profile clinically relevant, active B cell responses in patients receiving successful treatment and, in turn, develop a portfolio of antibody therapeutics against novel tumor targets with the potential to treat large patient populations. Atreca seeks talented, driven individuals who are dedicated to making a positive impact on human health and are motivated to become key members of a growing biotechnology company.

Position Summary

The (Sr.) Research Associate will work assisting the in vivo preclinical studies and the breeding of mouse colony in Atreca’s oncology research program. In this role, the RA/SRA will oversee the in-house mouse breeding colony and perform multiple efficacy studies testing various therapeutic agents in mouse tumor models. A successful candidate will rely on their expertise to initiate and measure tumor progression, administer therapeutics, and document their effects on tumor growth. This position will have the opportunity to interact and collaborate with a multidisciplinary team in a dynamic scientific environment.  Job title and compensation commensurate with experience and qualifications.

Duties and Responsibilities

  • The RA/SRA will oversee the in-house mouse breeding colony and perform multiple efficacy studies testing various therapeutic agents in mouse tumor models.
  • Perform in vivo studies to evaluate anti-cancer efficacy of test agents in tumor mouse models
  • Monitor mice groups enrolled in drug efficacy and mechanism of action studies
  • Perform drug dosing by various routes of administration
  • Monitor in-life study measurements: tumor volume, body weight, tracking overall health condition and survival of mice
  • Manage in-house mouse breeding colony
  • Entering data in animal management software
  • Availability to work on weekends on a rotating schedule
  • Follow laboratory safety guidelines and best practices

Required Skills and Qualifications

  • BS in Biology or related field with 2+ years of direct experience with mouse syngeneic and/or xenograft tumor models in a commercial or academic vivarium
  • Experience with mouse syngeneic and/or xenograft tumor models in a commercial or academic vivarium
  • Experience with orthotopic tumor models is desirable (models of renal cell carcinoma, colorectal cancer and mammary carcinoma)
  • Experience with tasks related to efficacy studies: tumor cell implantation, tumor volume measurement, blood draws (survival and terminal bleed), necropsy and tissue collection and processing
  • Experience with dosing of therapeutic agents by various routes of administration (IP, oral gavage and IV)
  • Experience with mouse breeding colony
  • Excellent organizational skills and ability to collaborate with Atreca’s scientific team
  • Proficiency in animal welfare and overall knowledge of federal guidelines for animal care and use
  • Ability to follow instruction and meticulous at data collection
  • Reliable team player, capable of managing time and assignments in a fast-paced research environment
  • Reliable, hardworking, and strong work ethnics
  • Transparent and open communication is a must
  • Strong analytical and presentation skills are desirable