AbbVie

Associate Scientist II/ Scientist I, Parkinson's Disease

Employer
AbbVie
Location
Cambridge, MA, United States
Posted
Aug 24, 2020
Ref
2004703
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie is investing heavily in a new research enterprise in Cambridge, Boston - the Foundational Neuroscience Center (FNC). The FNC is investigating the fundamental biological mechanisms underpinning neurodegenerative diseases, initially Alzheimer's disease. We are now growing our research remit to take advantage of shared disease mechanisms, building a new research team focused on Parkinson's disease (PD) to discover and develop disease-modifying therapeutics for this devastating disease.

We are seeking a highly motivated Associate Scientist with expertise in cellular/molecular biology to join the Parkinson's Biology Area team! As member of our team, you will work closely with the research team to develop in vitro models and to validate novel drug discovery targets, as well as identify and characterize drug leads and candidates.

Key Responsibilities Include:

  • Establish strong scientific and technical initiatives and hands-on implementation for new in vitro models
  • Execution of in vitro experiments to create cellular models in immortalized cell lines, primary neurons and/or iPSC-derived neurons
  • Build and execute biochemical and cell-based assays to support novel PD target validation
  • Collaborate with and support cellular and molecular biologists, in vivo pharmacologists and medicinal chemists across global research sites
  • Present research at internal meetings


Qualifications

Qualifications:

Position will be hired based on level of experience.

  • Bachelors or master's degree in molecular biology, with typically 3-5+ (BS), 0-2+ (MS) years of experience; Pharmaceutical industry experience preferred
  • High level of expertise with gene transfection (conceptualization, vector design and execution), clonal cell line selection and maintenance
  • Proficiency with standard cell and molecular biology, biochemistry, enzymology and neuroscience techniques including gene transfer methods, microscopy and high-content imaging, protein detection & quantification (such as ELISA, MSD), and enzyme kinetic assays
  • Extensive bench research experience and enjoy a laboratory-focused role in a fast-paced, multidisciplinary team
  • Ability to design, execute and interpret experiments independently
  • Excellent written and verbal communication
  • Strong interpersonal and teamwork skills paired with a strong work ethic
  • Strong organizational skills that enable multitasking and working within timelines
  • Background in cell biology, neuroscience and/or neurodegenerative disease mechanisms (protein aggregation etc.) considered a plus


Significant Work Activities
N/A
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
IC
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.