Research Associate II, Discovery Biology
- Employer
- MyoKardia, Inc (acquired by BMS)
- Location
- Brisbane, California, United States
- Start date
- Aug 22, 2020
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- Discipline
- Science/R&D, Biology, Research
- Required Education
- Bachelors Degree
- Position Type
- Full time
Job Details
We are seeking a highly motivated and diligent Research Associate II with cell biology background to join the Department of Biology in Myokardia. The successful candidate will be a member of the Discovery Biology group performing compound testing in cell-based and biochemical assays to support LO activities and HTS hits follow-up.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Performing cell-based and biochemical assays to test small molecular compounds
- Standard cell culture support including maintaining and plating of cells
- Instrument and assay troubleshooting support
- Data analysis and report generation
- Documentation of experimental procedure and result in laboratory notebook
- Presentation of experimental result in group setting
- Lab supply and equipment maintenance
- Interaction with CRO as needed
- Work collaboratively in a cross-functional team environment
EDUCATION/EXPERIENCE/SKILLS:
Education:
- BS or MS degree in biology, biochemistry or other related life science field
Experience:
- 2-5 years of experience in developing and performing cell-based and biochemical assays in microtiter plate format.
- Minimal 1 year of work experience in drug discovery of pharmaceutical/biotech industry
- Hands on experience of mammalian cell culture, stable cell line maintenances and cell plating. Prior work experience with IPS-derived cardiomyocyte is desired
Technical Skills:
- Lab automation equipment and plate readers, e.g., Bravo, Viaflo 384, FDSS uCell, Envision, SpectraMax M5,
- Data analysis: PowerPoint, Word, Excel, Prism, SoftMax Pro
- Knowledge of ion channel and GPCR receptor.
Behavioral Competencies:
- Strong organizational and time-management skills, thorough record-keeping skills, excellent interpersonal, verbal and written communication skills
- Accountable, detail-oriented and quality-focused
- Independent, self-motivated, and works well in a highly collaborative and team-oriented environment
Company
MyoKardia’s mission is to change the world for people with serious cardiovascular disease through bold and innovative science. MyoKardia is a clinical-stage bio pharmaceutical company discovering and developing targeted therapies for the treatment of serious cardiovascular diseases. The company is pioneering a precision medicine approach to its discovery and development efforts by 1) understanding the bio mechanical underpinnings of disease; 2) targeting the proteins that modulate a given condition; 3) identifying patient populations with shared disease characteristics; and 4) applying learnings from research and clinical studies to inform and guide pipeline growth and product advancement. MyoKardia’s initial focus is on small molecule therapeutics aimed at the proteins of the heart that modulate cardiac muscle contraction to address diseases driven by excessive contraction, impaired relaxation, or insufficient contraction. Among its discoveries are three clinical-stage therapeutics: mavacamten (formerly MYK-461); danicamtiv (formerly MYK-491) and MYK-224. Founded in September 2012 MyoKardia is headquartered in Brisbane, CA.
- Website
- http://www.myokardia.com/
- Phone
- 650-741-0900
- Location
-
1000 Sierra Point Parkway
Brisbane, CA 94005
US
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