Research Associate II/III, Logic-Gated CAR Cell Therapy

South San Francisco, California, United States
Aug 20, 2020
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Thank you for your interest in a career at Senti Biosciences. We are seeking individuals who are passionate about the future of genetic circuit therapeutics and have the energy and boldness to thrive and grow in a dynamic and fast entrepreneurial environment.

Complex diseases require smarter therapies, so we are seeking individuals who are passionate about joining a team to help create next generation cell therapies powered by highly targeted and dynamically controlled genetic circuits, to cure even the most challenging of diseases.

Senti Bio is seeking a highly motivated candidate to join our R&D team in developing innovative chimeric antigen receptor (CAR) cell therapies for treating cancer patients in need. A successful applicant will be comfortable performing high-risk/high-impact research, work collaboratively across various projects to meet milestones, and help maintain a positive and productive work culture as the company continues to grow.

    • Collaborate closely within and between R&D teams to efficiently perform experiments.
    • Perform in vitro studies to evaluate the efficacy of next generation logic-gated CAR immune cell therapies against cancer.
    • Perform flow cytometry-based cytotoxicity and ELISA-based cytokine assays on a regular basis.
    • Useful cell engineering experience includes: cell culture, banking of cryopreserved cells, virus production, and transduction of immune cells. Previous experience engineering immune cells to express CARs is a plus.
    • Adhere and optimize SOPs to ensure study integrity and quality.
    • Maintain accurate experiment records in various internal databases and perform basic data analyses.
    • Analyze and present data in team and project meetings.
    • Willingness to take on other duties to support the team.
    • Train other research staff as needed.

    • Bachelor's degree in life sciences or related discipline with 2+ years of experience in a laboratory setting. Industry experience is a plus.
    • Ability to learn and independently perform SOPs commonly employed by the team.
    • Excellent organizational and documentation skills.
    • Dedication to working in a team-oriented environment to contribute to shared projects.
    • Strong work ethic, self-motivation, and ability to multi-task in a fast-paced work environment.
    • Excellent communication skills with an ability to effectively communicate with other research teams.

Salary and Benefits
    • Competitive compensation package and title commensurate with qualifications and experience in the South San Francisco Biotech market.
    • Significant growth opportunity as the company expands.

Senti Bio is the next generation therapeutics company that designs gene circuits and programs cells for tremendous therapeutic value. Our mission is to engineer an entirely new class of medicine that will transform people's lives by curing the most challenging diseases. We are proud to count NEA, 8VC, Amgen Ventures, Pear Ventures, Lux Capital, Menlo Ventures, Allen & Company, Nest.Bio , Omega Funds, Goodman Capital, and LifeForce Capital among their investors. Senti Bio is based in South San Francisco, CA, USA.