Sr. Research Associate, Immunohistochemistry

Location
94080, South San Francisco
Posted
Jul 10, 2020
Ref
20-01628
Required Education
Bachelors Degree
Position Type
Full time

Sr. / Research Associate II, Immunohistochemistry and Analytical Histology
SSF, CA


We are seeking to hire a research associate, with experience in histology, immunohistochemistry, and imaging. This group plays a critical and central role supporting programs which are developing innovative drugs for our exciting emerging biology. A successful candidate will have strong experience in experimental design, tissue handling, immunohistochemistry and digital quantitative analysis of histological images all supported by a solid background in histological technique and theory.

Responsibilities:

  • Experimental design of histology experiments.
  • Perform histological stains, IHC / IF, or ISH on mouse and human tissue utilizing both manual and automated platforms.
  • Slide imaging and fluorescence microscopy.
  • Image quantification and analysis.
  • Database organization and oversight.
  • Experimental write up and communication.


Requirements:

  • Bachelor's or associate's degree in medical technology, clinical laboratory, chemical, physical or biological science and at least 4 years relevant work experience.
  • Experience processing, embedding, and sectioning FFPE tissues for IHC or ISH analysis, although this is not a large part of our day (as we send our sectioning out to a company). The knowledge and understanding of how that works is important to guiding our researchers in the best tissue handling protocols.
  • At least four years of experience performing immunohistochemistry by manual or automated methods on paraffin-embedded tissue.
  • Experience with IHC autostainers. Roche Ventana and / or Leica Bond experience a plus.
  • Familiarity with multiplexing, both bright field and fluorescent labels.
  • Familiarity with ISH (knowledge of the ACD platform is a plus).
  • Experience with slide scanning. Zeiss Axioscan Z1 experience a plus.
  • Proficiency with histological image analysis and statistical analysis, experience with image quantification tools such as Visiopharm is a plus.
  • Accurate documentation skills and the ability to comply with regulatory requirements.
  • Excellent communication, critical thinking, and problem-solving skills.