Sr Manager,/Associate Director, Project Management: 2020-86

Mirati Therapeutics (NASDAQ: MRTX) is a San Diego-based clinical-stage biotechnology company dedicated to advancing novel therapeutics that extend the lives of patients by directly addressing the genetic and immunological drivers of cancer. Mirati is developing sitravatinib, designed to selectively target a spectrum of tyrosine kinases implicated in both tumor growth and the suppression of immune responses to tumors. Sitravatinib has demonstrated durable responses in lung cancer patients whose cancer has progressed despite treatment with checkpoint inhibitors - an area of significant unmet medical need. Sitravatinib is being evaluated in multiple clinical trials to treat patients who are refractory to prior immune checkpoint inhibitor therapy, including a potentially registration-enabling Phase 3 trial of sitravatinib in combination with a checkpoint inhibitor in non-small cell lung cancer (NSCLC) that is currently enrolling patients.

Mirati is also developing novel direct inhibitors of KRAS mutations including MRTX849, a potent and selective inhibitor of KRAS G12C. This historically difficult to drug target is present in approximately 14% of NSCLC adenocarcinomas, 4% of colorectal cancer as well as smaller percentages of several other difficult-to-treat cancers. MRTX849 is being evaluated in a Phase 1/2 clinical trial as a treatment for patients with KRAS G12C-positive tumors. Our research on G12C has led to breakthroughs in targeting other KRAS mutations including G12D which drives tumor growth in more patients than G12C and includes pancreatic, colorectal and other types of cancer.

We are Mirati

Our mission is to discover, design, and deliver breakthrough therapies to transform the lives of cancer patients and their loved ones. We have built a culture fueled by accountability, urgency, collaboration and open-mindedness, and have established ourselves as an innovator within our industry. As we grow, we are looking to build diverse teams, with skilled individuals that are passionate about their work.

Why join us?

The Sr Manager/Ass Director of Project Management will strategically lead the optimal global development of an asset, advancing programs through all stages of clinical development and life-cycle management. This role will work with various stakeholders across Mirati and will help define and outline a strategic vision. This role will apply a strong project management discipline to lead the establishment of detailed operational plans in alignment with corporate strategies and financial metrics across the continuum of research, development and commercial. With experience in cross-functional team management, the Project Manager provides end-to-end oversight of the asset lifecycle activities across all working groups to align with corporate goals and objectives.

Responsibilities:

• Leads teams to develop and recommend the asset level strategy to senior leadership, incorporating clear goals, milestone timing and budget considerations
• Accountable for overseeing the creation of the asset development plan and the associated functional development plans
• Leads teams to identify challenges and risks and to develop and propose contingency plans to mitigate risks in a proactive and timely manner
• Manages the day-to-day execution of integrated cross-functional team activities to meet or exceed annual program and corporate goals
• Creates and embeds core processes, metrics and holds others accountable to timelines, data and advancing the asset
• Promptly escalates barriers to project delivery, particularly related to resource shortfall, performance issues, process inefficiencies, or other environmental factors
• Drives preparation of governance board deliverables and ensure implementation of decisions
• Monitors and institutes corrective measures to ensure team health remains solid
• Ensures alignment between project plans, functional stakeholders and alliance partners as required
• If applicable, liaises with the Director, Alliance Management to ensure delivery of alliance goals
• If applicable, conducts and manages routine alliance partnership meetings as they pertain to project/program delivery
• Utilize databasing tools to track detailed level project plans into Mirati's authoritative system for project planning and reportingIdentifies and aligns resources (people and financial), team objectives and strategies behind the vision to ensure successful project completion
• Works to resolve disputes among teams and create a positive work environment and team culture
• Applies project management best practices in the development, initiation, planning, execution, control, and closing of projects
• Position may include supervisory responsibility

Requirements:

• BS or BA in a scientific discipline required; an advanced degree or PMP certification preferred
• 12+ years of experience in the biopharmaceutical industry with focus on Oncology
• 5+ years of experience leading multi-disciplinary development teams in the execution of operational plans; ideally across multiple functional areas and various development phases
• Proven project management and leadership experience/training
• Must possess exceptional organization and communication skills
• Strong understanding of drug development strategies, across all critical product development disciplines (nonclinical, clinical, CMC, RA/QA)
• Strong interpersonal skills and business acumen, excellence in building and managing relationships, ability to understand all perspectives, find common ground and effectively bridge significant differences
• Detail-oriented while also retaining the ability to see the big picture
• Demonstrated problem solving skills with strong business skills/acumen
• Proven ability to manage multiple projects, set priorities and meet deadlines
• Experience working on cross-functional teams to accomplish shared goals
• Requires flexible work schedule to accommodate program priorities as needed
• Some travel may be required (10-15%)

Mirati's policy is to provide equal employment opportunities to all applicants and employees without regards to race, color, religion, creed, gender identity or expression, age, national origin or ancestry, citizenship, disability, sexual orientation, marital status, pregnancy, veteran status, membership in the uniformed services, genetic informations, or any other basis protected by applicable law.

Notice to Third Party Agencies: Please note that Mirati Therapeutics Inc. does not accept unsolicited resumes from recruiters or employment agencies.