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Research Investigator, Discovery Biology

Employer
Black Diamond Therapeutics, Inc.
Location
New York, NY, US
Start date
Feb 16, 2020

View more

Discipline
Regulatory, Research/Documentation, Science/R&D
Required Education
Doctorate/PHD/MD
Position Type
Full time

Job Details

Overview

Black Diamond Therapeutics is a precision oncology medicine company pioneering the discovery and development of small molecule, tumor-agnostic therapies. Black Diamond targets undrugged mutations in patients with genetically defined cancers for whom limited treatment options currently exist. Black Diamond is built upon a deep understanding of cancer genetics, protein structure and function, and medicinal chemistry. The Company's proprietary technology platform, Mutation-Allostery-Pharmacology, or MAP, platform, is designed to allow Black Diamond to analyze population-level genetic sequencing data to identify oncogenic mutations that promote cancer across tumor types, group these mutations into families and develop a single small molecule therapy in a tumor-agnostic manner that targets a specific family of mutations.

Black Diamond has an immediate need for a Research Investigator - Discovery Biology . Reporting to the Director of Discovery Biology, the incumbent will drive drug discovery projects through close collaboration with others to reshape and extend the pipeline of precision oncology medicines.

Responsibilities

  • Lead a biology drug discovery team to validate novel allosteric oncogenes and execute biology screens to effectively drug allosteric oncogene targets
  • Participate in a multi-disciplinary team of biologists and chemists to progress programs.
  • Staying abreast of the latest scientific and competitive developments and applying knowledge to project strategy.
  • Prepare and present hypotheses, on-going progress reports, technical reports and future planning (including contributing to budgets and business plans)
  • Contribute to building a culture that embraces scientific excellence and integrity with a sense of urgency and collaboration with key stakeholders.


Qualifications

  • PhD. in biochemistry, cell biology, pharmacology or a related scientific field
  • 2-5+ years of experience in drug discovery in a pharmaceutical and/or biotech environment
  • Experience working with cross-functional teams

Work Environment :

This job operates in a professional office environment. This role routinely uses standard office equipment.

Physical Demands :

The physical demands described here are representative of those that must be met by an employee to successfully perform he essential functions of this job.

While performing the duties of this job, the employee is occasionally required to stand; walk; sit; used hands to fingers, handle, or feel objects, tools, or controls; reach with hands and arms; climb be stairs; talk or hear. The employee must occasionally lift or move office products and supplies, up to 20 lbs.

Company

Our Vision
Precision Cancer Medicines for Every Genetically-Defined Patient    
 
Company Overview
Black Diamond Therapeutics: A Next-Wave Cancer Precision Medicine Company
 
Black Diamond Therapeutics has pioneered the development of selective medicines for patients with genetically-defined cancers driven by oncogenes activated by allosteric mutations.
 
The cornerstone of our approach derives from evolving trends in cancer clinical medicine. Genome-wide information – now routinely obtained from DNA testing of cancer patients – identifies clusters of uncharacterized genomic alterations. Today, new baskets of un-drugged oncogenic targets exist, leading to the identification of additional cancer patients in need of novel therapies.
 
Using our MAP platform, Black Diamond Therapeutics is pioneering new ways to functionally assess the mutational landscape of individual oncogenes – to discover and validate new targets, and to develop novel approaches to creating highly selective therapeutics.

Company info
Website
Location
One Main Street
Cambridge
MA
02142
United States

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