Scientist/Sr. Scientist, Cancer Immunology

Responsible for collaboratively leading and conducting research on drug targets and pathways that enhance anti-tumor immune responses.

Good things are happening at Omeros!

Come join our discovery Team!

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market as well as orphan indications targeting inflammation, complement-mediated diseases and disorders of the central nervous system.

The company's drug product OMIDRIA® (phenylephrine and ketorolac injection) 1% / 0.3% is marketed in the U.S. for use during cataract surgery or intraocular lens (IOL) replacement to maintain pupil size by preventing intraoperative miosis (pupil constriction) and to reduce postoperative ocular pain. In the European Union, the European Commission has approved OMIDRIA for use in cataract surgery and other IOL replacement procedures to maintain mydriasis (pupil dilation), prevent miosis (pupil constriction), and to reduce postoperative eye pain.

Omeros has multiple Phase 3 and Phase 2 clinical-stage development programs focused on: complement-associated thrombotic microangiopathies; complement-mediated glomerulonephropathies; Huntington's disease and cognitive impairment; and addictive and compulsive disorders. In addition, Omeros has a diverse group of preclinical programs and a proprietary G protein-coupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and corresponding compounds, a number of which are in preclinical development. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

• Work with the Discovery Research team to enhance our understanding of the role of specific GPCRs in anti-tumor immune responses and overall immune function

• Leverage, develop and execute in vivo models of human and murine tumor growth and anti-tumor immunity

• Leverage, develop and execute in vitro systems to evaluate the effects of GPCR-targeting compounds on innate and adaptive immune cell function

• Execute experiments, data analysis, interpretation, and planning both independently and collaboratively

• Manage and archive data

• Present experimental results and interpretations at project meetings

• Present at scientific conferences and participate in manuscript writing

• A PhD in Cancer Biology or Immunology with 3+ years of postdoctoral experience in similar fields

• A broad understanding of solid tumor biology and cancer immunology

• First-hand experimental expertise in various animal models of cancer and immunotherapy

• A current understanding of the tumor microenvironment and the cellular and molecular biology of cancer

• Demonstrated troubleshooting skills in optimizing and developing experimental methods

• Familiarity with computer applications including word processing, spreadsheets, database management, and presentation software

• Excellent interpersonal written and verbal communication skills

• Time management skills

• Problem-solving skills

• Demonstrated ability to build and maintain positive relationships with management, peers, and subordinates

• Demonstrated ability to work in a team-oriented, highly motivated environment including the ability to foster collaboration

• Demonstrated ability to present scientific results to project teams and management

• Ability to handle several priorities simultaneously

• Integrity

• This position may require some work on weekends and holidays

• Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.

• May encounter prolonged periods of sitting or standing

• This position requires working around hazardous materials

If you have the skills, knowledge and experience we are looking for, we'd love to hear from you!

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000.