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Data Scientist / Senior Data Scientist, Human Genetics

Employer
Maze Therapeutics
Location
South San Francisco, CA
Start date
Nov 7, 2019

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Discipline
Information Technology, Business/Data Analytics, Science/R&D
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay
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Job Details

We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly-growing startup on our mission to translate novel genetic insights into lifesaving medicines. We are integrating human genetics and functional genomics to decode the mysteries of genetic modifiers, leading us to new medicines we'll develop for a range of severe diseases.

We are seeking a talented and highly motivated scientist to help build and apply our genetics discovery platform. The successful candidate will join a team of data scientists, computational biologists, systems architects and automation engineers to mobilize genetics and functional genomics data towards the discovery of new therapeutic targets and drugs.

Your Role in Navigating The Maze:
  • Contribute to designing and building the data and computational ecosystem for the company's R&D efforts
  • Responsible for managing and integrating human genetics data from public and proprietary sources
  • You will work with the Human Genetics department to implement production-quality, cutting-edge data management, analysis and visualization tools
  • Contribute to building production-quality, scalable bioinformatics and genetics pipelines
  • Build and maintain relationships with external collaborators to obtain and manage complex genetics data
  • Communicate data and scientific results to both internal and external audiences, and will contribute to open-source and collaborative projects

Your Navigation Tools:
  • Advanced degree (or equivalent experience) in human genetics, computational biology, bioinformatics or other scientific field that has relevance to high-dimensional biological data
  • Extensive familiarity with genotyping and sequencing technologies (including alignment, variant calling and annotation methods), and with pipelines for analyzing genotype and phenotype data (PLINK, HAIL)
  • Extensive experience in the use of a high-level programming language (particularly R/Bioconductor, Python/Pandas or C/C++)
  • Experience with large biobank resources (e.g., UK biobank) or data aggregators (e.g., Open Targets)
  • A demonstrated ability to understand scientific needs from multiple functions and an eagerness to work in a fast-paced, highly matrixed environment; experience working and communicating with scientific teams; strong communication, data presentation and visualization skills
  • A detail-oriented approach to projects, experience with troubleshooting and optimizing data and software systems and a demonstrated drive to raise the bar with every project
  • Experience with statistical modeling and machine learning a plus

If you're ready to Enter The Maze, send your resume to careers@mazetx.com .

Maze Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Company

Maze Therapeutics is translating novel genetic insights into lifesaving medicines, through an approach that integrates human genetics and functional genomics. Advances in these areas have enabled us to decode the mysteries of genetic modifiers in a range of severe diseases, which we aim to turn into medicines that mimic protective mutations. 
 
What are genetic modifiers?
 
Despite an understanding of the genetic basis for many diseases, it remains a mystery why some people with a disease-causing mutation never get sick. This is often due to genes elsewhere in our DNA that affect the severity of disease and can provide a natural form of protection.
 
The Maze approach
 
Dramatic advances in human genetics and functional genomics now enable us to decode the mysteries of genetic modifiers in a range of severe diseases. Today, we believe we can systematically identify genetic modifiers and turn these insights into medicines. We have assembled a world-class team to realize this vision, including creative scientific pioneers, experienced company builders and biotech industry leaders.
 
Join us in our pursuit to change lives by translating genetic insights into medicine - view our job postings with the link to the left.

Company info
Website
Location
171 Oyster Point Blvd, Suite 200
 South San Francisco
CA
94080
United States
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