Scientist I- Mass Spectrometry
- Employer
- Frederick National Laboratory for Cancer Research
- Location
- Frederick, MD, USA
- Start date
- Nov 7, 2019
View more
- Discipline
- Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- BioCapital
Job Details
KEY ROLES/RESPONSIBILITIES
- Support a range of NCI RAS Initiative projects encompassing global, targeted, and/or quantitative proteomics
- Assist with sample preparation and data acquisition/analysis for bottom-up and middle-down proteomic applications
- Assist with method development for improved proteoform characterization and PTM localization on an Orbitrap Fusion Lumos
- Contribute to RAS proteoform assay expansion to encompass a broad range of cell, tissue, and cancer contexts
- Support the daily operation and routine maintenance of three Orbitrap-based mass spectrometers and accompanying LC platforms
- Report, present, and publish research findings
BASIC QUALIFICATIONS
- Possession of a Ph.D. degree in Chemistry, Biochemistry, Molecular Biology, or a related field from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
- Prior experience in sample preparation, data acquisition, and data analysis for tandem MS/MS and/or top-down proteomics (with accompanying publication record)
- Demonstrated ability to independently carry out experimental procedures, balance changing priorities, and perform troubleshooting to ensure timely project completion
- Ability to master novel technologies, workflows, and instrumentation
- Must be able to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
- Prior experience in top-down proteomic applications (global and targeted), instrumentation, and data analysis
- Prior experience in protein purification, protein biochemistry, and molecular biology
- Prior experience in operating and maintaining Orbitrap-based instruments
JOB HAZARDS OR REQUIREMENTS
- Candidate will be working with or have the potential for exposure to infectious material(s) or Other Potentially Infectious Materials (OPIM), requiring medical clearance and immunization in accordance with protocol requirements
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
Company
A rewarding career with global impact
Whether you’re an expert in your field or just starting out, we have a career opportunity for you. We’re always looking for people to join us in fulfilling the mission of the Frederick National Laboratory: discovery, innovation, and success in the biomedical sciences.
Our team of 2,400+ scientists, technicians, administrators, and support staff work at the forefront of basic, translational, and preclinical science, with a focus on cancer, AIDS, and other infectious diseases.
We collaborate with colleagues across the National Cancer Institute, National Institutes of Allergy and Infectious Diseases, and others throughout the National Institutes of Health. We also engage with extramural investigators in academia, government and industry.
Your path to joining our team begins with the desire to work for the only national laboratory dedicated to biomedical research. Our employees share a common desire to help make a difference in cancer research and public health concerns. As you search for a career that fits your education, skills, and abilities, explore the core values that guide us and emphasize work-life balance.
Discover why joining the Frederick National Laboratory team could be the most important career step you take
- Website
- https://frederick.cancer.gov/
- Phone
- 301-846-1000
- Location
-
8560 Progress Drive
Frederick
MD
21701
US
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