Undergrad Co-op - R&D (PKDM/Drug Transporters)

Amgen discovers, develops and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science's promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to improve people's lives dramatically.

The Discovery Technologies department at our Cambridge, Massachusetts location is looking for an undergraduate interested in a 6-month co-op placement. The Co-op - R&D (Pharmacokinetics and Drug Metabolism) will support the drug transporter team on a project which will focus on establishing and validating transporter inhibitory studies that will help understand the potential of small molecules to generate clinically relevant drug-drug interactions. The co-op will work closely with experienced transporter scientists to design and conduct transporter inhibition experiments and analyze and interpret the study results. With this role, the co-op will have an opportunity to work on a variety of cell-based assays and explore routinely used methodologies to assess the perpetrator potential of small molecules. The co-op will also gain experience in applying the study data to FDA recommended models to evaluate the likeness of small molecules to exhibit drug-drug interactions in a clinical setting.

Amgen Cambridge's Dept. of Pharmacokinetics and Drug Metabolism (PKDM) seeks a qualified co-op with the following job responsibilities:

• Culture and maintain transporter over expressing cell lines.
• Evaluate transporter inhibitory effects of small molecules using a variety of cell-based radioactive assays.
• Troubleshoot assays and provide solutions to resolve technical gaps and methodologies, if any.

Relocation in the form of a miscellaneous allowance will be provided for eligible candidates.

Basic Qualifications

Amgen requires that all individuals applying for an undergraduate internship or an undergraduate co-op assignment at Amgen must meet the following criteria:

18 years or older

Currently enrolled in a full time Bachelor's Degree program from an accredited college or university with a 3.0 minimum GPA or equivalent

Completion of one year of study from an accredited college or university prior to the internship commencing

Enrolled in a full time Bachelor's degree program following the potential internship or co-op assignment with an accredited college or university

Must not be employed at the time the internship starts

Preferred Qualifications

Degree concentration(s) in Life Sciences, Biology, Bioengineering or related fields

Knowledge in cell culture and cell-based assays

Experience with radiometric assays and analysis

Experience in implementing, optimizing and troubleshooting cell-based assays

Proficiency in Excel, Word and PowerPoint

Strong interpersonal, communication and collaborative skills

Only candidates who apply via http://careers.amgen.com/ will be considered. Please search for Keyword 83897.

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Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.