Sr. Scientist, Cell Engineering & Characterization

Job Description

We are a global biopharmaceutical leader with a diverse portfolio of prescription medicines, oncology, vaccines and animal health products.

We are driven by our purpose to develop and deliver innovative products that save and improve lives. With 69,000 employees operating in more than 140 countries, we offer state of the art laboratories, plants and offices that are designed to Inspire our employees as we learn, develop and grow in our careers.  We are proud of our 125 years of service to humanity and continue to be one of the world’s biggest investors in Research & Development.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

INVENT.

IMPACT.

INSPIRE.

The Cell Line Development under Biologics Process R&D is seeking a highly motivated and experienced Senior Scientist to support biopharmaceutical commercial cell line development and the innovative therapeutic cell engineering projects. The successful candidate should have an in-depth understanding of immunology, stem cell biology, molecular biology, and TCR signaling with working experience in next-generation sequencing (NGS) data analysis and and integration of ‘omics’ data. Ideal  candidate should have hand-on experience in primary  cell culture, gene editing and functional testing of engineered mammalian cells, i.e. primary T and other hematopoietic cells, ES cells, iPSCs, as well as general suspension tissue culture experience such as using CHO cells, etc.  Candidate should demonstrate and stay up to date on the knowledge of principles and theories related to new and emerging technologies. The selected candidate will be expected to work independently, including proactive planning, trouble shooting and successful execution of complex experimental protocols. The selected candidate will be developed to serve as a technical lead and functional area representative on project teams. 

Education Minimum Requirement: 

• PhD in Immunology, Virology, Genetics, Bioinformatics, or related Biological Sciences with at least 2 years of the experience in cell-based assay development.

Required Experience and Skills: 

• A demonstrated foundational understanding of immunology and molecular biology.
• Experienced in primary cell isolation and culture. 
• Experienced in multi-color flow cytometry and cell surface marker analysis. 
• Expertise in immunological assays related to T cell signaling and cellular functions.
• Creative. Critical thinking. Strong troubleshooting skills.
• Strong attention to detail with the ability to multi-task and handle multiple responsibilities simultaneously.
• Ability to work independently and as part of a team.

Preferred Experience and Skills:

• Experienced with virus production and viral-based gene transduction methods
• Experienced in iPSC generation and stem cell culture.
• Experienced in NGS, single cell sequencing, transcriptomics and current bioinformatics data analysis tools. 
• Experienced in gene editing and gene delivery technologies.
• Experienced in microscopy techniques and assays such as confocal microscopes and high content imaging.
• Expertise of database and statistical software (e.g. Excel, JMP)
• Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines.

If you need an accommodation for the application process please email us at staffingaadar@merck.com

For more information about personal rights under Equal Employment Opportunity, visit:

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OFCCP Pay Transparency Rule

We are an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

DMSO, Phenol, Bacterial

Number of Openings:

1

Requisition ID:PRE000741