Biologist-Immunology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
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Responsibilities

The Immunology research group focuses on discovering innovative biotherapeutic medicines treating autoimmune diseases and related complications. We are seeking a highly motivated and dedicated scientist with knowledge and experience of cellular and molecular immunology, who also shares our passion to help patients live with higher quality of life. Our team works in a dynamic and collaborative environment. Are you skilled at in vitro cell-based assays? The focus of our work is to independently design, develop and validate the immunology cell-based functional assays to test and analyze molecule activities, investigate the mechanism of action of biological drugs, evaluate performance in various animal disease models, and ultimately to deliver preclinical evidence for future clinical testing.
Key Objectives/Deliverables:

• Develop immune functional cell-based assays using immunology technologies (e.g. primary human and mouse lymphocytes, myeloid cell activation and differentiation, cytokine assays, multiple color flow cytometry).
• Screen and analyze data for protein or small molecule drugs.
• Investigate cellular signal transduction, develop cellular activity assays, cytokine/receptor signaling (western, qPCR, intracellular staining, confocal/image related techniques).
• Evaluate therapeutic molecules to provide efficacy evidence to advance molecule.
• Isolation, purification and culture of different freshly isolated populations of human and mouse blood cells for in vitro assays.
• Preparing cellular materials for genomic and proteomic assessment.
• Independently design and execute experiments, analyze, interpret and present experimental data.
• Adherence to good research practices, and laboratory e-notebook maintenance

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53087BR

Basic Qualifications

• Bachelor of Science degree in biology, molecular and cellular immunology or a related biological area

Additional Skills/Preferences

• Prior experience in an academic institute or pharmaceutical industry preferred
• Extensive research experience of immunology, molecular biology as well as proteomic and genomic technologies.
• Understand and have experience with various in vivo animal autoimmune or inflammatory disease models

Additional Information
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status